Effects of supercooling and organic solvent on the formation of a silk sponge with porous 3-D structure, and its dynamical and structural characterization using solid-state NMR
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A widely accepted feature of the silk generated by silkworms is its impressive mechanical properties. Aside from its direct use as silk fibers, silk protein can also be dissolved and converted into hydrogels , films , fibers , beads , electrospun nonwoven fibroin , and sponges, leading to great versatility in use. Silk sponge is the generic name for the porous 3-D structure made of silk fibroin. Many methods have been explored for the formation of a silk sponge. Freeze-drying of fibroin hydrogels  or fibroin solution in the presence of an appropriate cross-linker  yields silk sponges. Salt leaching and gas foaming are also used to form silk sponges [7, 8]. Silk sponges can also formed by repeated freezing and thawing .
KeywordsNuclear Magnetic Resonance Sponge Silk Fibroin Random Coil Random Coil Structure
This study was supported in part by the Agri-Health Translational Research Project and Research and development project for application in promoting a new policy for Agriculture Forestry and Fisheries.
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