Journal of Materials Science

, Volume 44, Issue 16, pp 4394–4398 | Cite as

Comparison of Ca/P mineralization on the surfaces of poly (ε-caprolactone) composites filled with silane-modified nano-apatite

  • Chi DengEmail author
  • Nin Yao
  • Xiong Lu
  • Shuxin Qu
  • Bo Feng
  • Jie Weng
  • Xiaobing Yang


This study aims to comparatively investigate the Ca/P mineralization on the surfaces of poly (ε-caprolactone) (PCL) composites with apatite nano-fillers, which were modified with silane coupling agents. Three kinds of silane coupling agents like 3-Methylacryoxypropyltrimethoxy silane (KH560), γ-Methacryloxypropyltrimethoxy silane (KH570), and N-(β-aminoethyl)-γ-aminopropyltrimethoxy silane (KH792) were firstly employed to modify the surfaces of nano-apatite particles, and then silane-modified nano-apatite/PCL composites were prepared by combining solvent dispersion and melting co-blending with hot-pressing methods. The Ca/P mineralization of the modified PCL-Matrix composites was evaluated by soaking in 2-time simulated body fluid (2SBF) at 36.5 °C and pH 7.40 after 21 days. These results showed that the Ca/P mineralization on the surface of the silane-modified composite was same as not modified composite. Apatite obtained on the surface of the modified composite film was of lower crystallinity, 1.62 Ca/P ratio and carbonate ceramic, similar to inorganic composition of bone in biological body, and not notably different from one of not modified PCL composite. This discussion revealed that as-fabricated silane-modified composite could achieve Ca/P mineralization and exhibited the ability of obtaining like-bone apatite on own surface like other bioactive materials.


Apatite Composite Film Simulated Body Fluid DMAc Silane Coupling Agent 



This project was financially supported by Scientific Research Fund of Sichuan Provincial Education Department (08ZA094) and the National Natural Science Foundation of China (No. 30700172), Specialized Research Fund for the Doctoral Program of Higher Education for Young Teacher (20070613019), National Key Project of Scientific and Technical Supporting Programs Fund from MSTC (2006BAI16B01).


  1. 1.
    Wang M (2003) Biomaterials 24:2133CrossRefGoogle Scholar
  2. 2.
    Yang R, Takahashi A, Wong CP (2003) Compos A Appl Sci Manuf 34:1113CrossRefGoogle Scholar
  3. 3.
    Huang J, Yu WL, Xiao WF et al (2007) J Mater Sci Mater Med 18:2151CrossRefGoogle Scholar
  4. 4.
    Chen BQ, Sun K (2005) Polym Test 24:978CrossRefGoogle Scholar
  5. 5.
    Lei Y, Rai B, Ho KH, Teoh SH (2007) Mater Sci Eng C 27:293CrossRefGoogle Scholar
  6. 6.
    Chen BQ, Sun K (2005) Polym Test 24:64CrossRefGoogle Scholar
  7. 7.
    Causa F, Netti PA, Ambrosio L et al (2005) J Mater Sci Mater Med 10:672Google Scholar
  8. 8.
    Yu SC, Kithva PH, Rajemdra K, Philip C, Khor KA (2005) Biomaterials 26:2343CrossRefGoogle Scholar
  9. 9.
    Silvio LD, Dalby M, Bonfield W (1998) J Mater Sci Mater Med 9:845CrossRefGoogle Scholar
  10. 10.
    Shor L, Guceri S, Wen XJ et al (2007) Biomaterials 28:5291CrossRefGoogle Scholar
  11. 11.
    Magnaldo AM, Champion R (2007) Chem Eng Sci 62:766CrossRefGoogle Scholar
  12. 12.
    Wong SC, Baji A (2008) J Mater Sci Mater Med 19:929CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2009

Authors and Affiliations

  • Chi Deng
    • 1
    • 2
    Email author
  • Nin Yao
    • 2
  • Xiong Lu
    • 2
  • Shuxin Qu
    • 2
  • Bo Feng
    • 2
  • Jie Weng
    • 2
  • Xiaobing Yang
    • 2
  1. 1.Institute of Silicon MaterialsLeshan Teachers CollegeLeshanChina
  2. 2.Key Lab of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and EngineeringSouthwest Jiaotong UniversityChengduChina

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