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Journal of Materials Science

, Volume 44, Issue 6, pp 1442–1448 | Cite as

TiO2 foams with poly-(d,l-lactic acid) (PDLLA) and PDLLA/Bioglass® coatings for bone tissue engineering scaffolds

  • Saša Novak
  • John Druce
  • Qi-Zhi Chen
  • Aldo R. Boccaccini
Syntactic and Composite Foams

Abstract

TiO2 foam-like scaffolds with pore size ~300 μm and >95% porosity were fabricated by the foam replication method. A new approach to improve the structural integrity of the as-sintered foams, which exhibit extremely low compression strength, was explored by coating them with poly-(d,l-lactic acid) (PDLLA) or PDLLA/Bioglass® layers. The PDLLA coating was shown to improve the mechanical properties of the scaffold: the compressive strength was increased by a factor of ~7. The composite coating involving Bioglass® particles was shown to impart the rutile TiO2 scaffold with the necessary bioactivity for the intended applications in bone tissue engineering. A dense hydroxyapatite layer formed on the surface of the foams upon immersion in simulated body fluid for 1 week.

Keywords

Foam Compressive Strength Rutile Simulated Body Fluid Bioactive Glass 

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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Saša Novak
    • 1
  • John Druce
    • 2
  • Qi-Zhi Chen
    • 2
  • Aldo R. Boccaccini
    • 2
  1. 1.Department of Nanostructured MaterialsJ. Stefan InstituteLjubljanaSlovenia
  2. 2.Department of MaterialsImperial College LondonLondonUK

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