Journal of Materials Science

, Volume 42, Issue 11, pp 4018–4024 | Cite as

Synthesis, characterization, and antibacterial activities of novel N-halamine copolymers

  • Ying Chen
  • Li WangEmail author
  • Haojie Yu
  • Quan Shi
  • Xiaochen Dong


The synthesis and antibacterial properties of N-halamine copolymers are reported in this paper. 3-(4′-vinylbenzyl)-5,5-dimethylhydantoin (VBDMH) monomer and its copolymers with n-butyl methacrylate (BMA) were prepared under mild conditions. The effects of monomer feeds on the composition of the final copolymers and reaction conversion were investigated. It was found that VBDMH had higher reactivities than BMA in the copolymerization reactions and the reactivity ratios of VBDMH and BMA were calculated to be 8.91 and 0.42, respectively, according to the Fineman–Ross equation in the preparation of PBMA-co-VBDMH. Two chlorination methods were applied and compared in the process of polymers chlorination. After chlorination by tert-butyl hypochlorite, the polymers provided powerful antibacterial activities against Escherichia coli (E. coli). The surface morphologies of the chlorinated polymer films used in antibacterial assessment were observed by scanning electron microscope. The copolymers before and after chlorination were characterized with fourier transform infrared (FTIR) and 1H-nuclear magnetic resonance (1H-NMR). Their thermal properties were analyzed with thermogravimetric analysis (TGA) studies.


Reactivity Ratio Sodium Hypochlorite Solution Hydantoin Initial Molar Ratio Final Copolymer 



The authors thank Yuanming Ying for performing the microbiological evaluation of the polymers.


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Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Ying Chen
    • 1
  • Li Wang
    • 1
    Email author
  • Haojie Yu
    • 1
  • Quan Shi
    • 1
  • Xiaochen Dong
    • 1
  1. 1.State Key Laboratory of Polymer Reaction Engineering, College of Materials Science and Chemical EngineeringZhejiang UniversityHangzhouChina

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