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Journal of Materials Science

, Volume 41, Issue 13, pp 4273–4284 | Cite as

Composition and crystal structure of resorbable calcium phosphate thin films

  • L. Tuck
  • M. Sayer
  • M. Mackenzie
  • J. Hadermann
  • D. Dunfield
  • A. Pietak
  • J. W. Reid
  • A. D. Stratilatov
Article

Abstract

Silicon stabilized tricalcium phosphate (Si-TCP) is formed, among other phases, as a result of sintering hydroxyapatite (HA) in the presence of silica (SiO2) at >800°C. Calcium phosphate films sintered at 1000°C on quartz substrates are examined with and without additional SiO2 added to the starting precipitate. Data from transmission electron microscopy (TEM) and X-ray photoelectron spectroscopy (XPS) separate the undoped film morphology into a surface layer with a monoclinic crystal structure P21/a characteristic of α or Si-tricalcium phosphate and grain size in the range 100–1000 nm and a substrate layer with a crystal structure which is predominantly apatitic P63/m and grain size in the range 30–100 nm. The silicon content is greatest in the substrate layer. The addition of SiO2 to the film material during fabrication induces a more uniform grain size of 10–110 nm and a higher Si content. The structural and phase evolution of these films suggests the nucleation of α-TCP by the local formation of Si-TCP at a SiO2-hydroxyapatite interface. The results are consistent with X-ray diffraction studies and are explained by a model of nucleation and growth developed for bulk powders.

Keywords

Calcium Phosphate Quartz Substrate Electron Energy Loss Spectroscopy Substrate Layer Tricalcium Phosphate 

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References

  1. 1.
    Q. QUI, P. VINCENT, B. LOWENBERG, M. SAYER and J. E. DAVIES, Cells Mater 3(4) (1993) 351.Google Scholar
  2. 2.
    S. LANGSTAFF, M. SAYER, L. WEAVER, S. PUGH and T. J. N. SMITH, Mat. Res. Soc. Proc. 414 (1996) 87.CrossRefGoogle Scholar
  3. 3.
    S. LANGSTAFF, M. SAYER, T. J. N. SMITH, S. M. PUGH, S. A. M. HESP and W. T. THOMPSON, Biomaterials. 20 (1999) 1727.CrossRefGoogle Scholar
  4. 4.
    S. LANGSTAFF, M. SAYER, T. J. N. SMITH and S. M. PUGH, Biomaterials. 22 (2001) 135.CrossRefGoogle Scholar
  5. 5.
    Millenium Biologix Inc, 785 Midpark Drive, Kingston, Ontario, Canada. K7M 7G3.Google Scholar
  6. 6.
    M. SAYER, A. D. STRATILATOV, J. REID, L. CALDRIN, M. J. STOTT, X. YIN, M. MACKENZIE, T. J. N. SMITH, J. A. HENDRY and S. D. LANGSTAFF, Biomaterials. 24 (2003) 369.CrossRefGoogle Scholar
  7. 7.
    A. PIETAK, M. SAYER and M. J. STOTT, J. Mater. Sci. 39 (2004) 1.CrossRefGoogle Scholar
  8. 8.
    J. REID, M. SAYER and T. J. N. SMITH, Mat. Res. Soc. Symp. Proc. 717 (2002) 11.Google Scholar
  9. 9.
    J. REID, A. PIETAK, M. SAYER, D. DUNFIELD and T. J. N. SMITH, Biomaterials (2004) (in press).Google Scholar
  10. 10.
    A. LE BAIL, H. DUROY and J. L. FOURQUET, Mat. Res. Bull. 23 (1988) 447.CrossRefGoogle Scholar
  11. 11.
    V. RODRIGUEZ, and J. RODRIGUEZ-CARVAJAL, J. Applied Cryst. (to be published).Google Scholar
  12. 12.
    D. DUNFIELD, J. Applied Cryst. (in preparation).Google Scholar
  13. 13.
    FULLPROF 2000, Rodríguez-Carvajal J, Laboratoire Léon Brillouin (CEA-CNRS) CEA/Saclay, 91191 Gif sur Yvette Cedex, France.Google Scholar
  14. 14.
    M. MATTHEW, L. SCHROEDER, B. DICKENS and W. E. BROWN, Acta Cryst. B33 (1977) 1325.CrossRefGoogle Scholar
  15. 15.
    Errors were calculated using correlated residuals: J. F. BERAR and P. LELANN, Appl. Cryst. 24 (1991) 1; J. F. BERAR, “Acc. in Pow. Diff. II.” NIST Sp. Pub. 846 (1992) 63.Google Scholar
  16. 16.
    D. DUNFIELD, L. CALDRIN, M. J. STOTT and M. SAYER, in “The powder refinementof α-tricalcium phosphate Ca3(PO4)2” (in preparation).Google Scholar
  17. 17.
    R. GIBSON, S. M. BEST and W. BONFIELD, J. Biomed. Mater. Res. 44 (1999) 422.CrossRefGoogle Scholar
  18. 18.
    TAKAFUMI, T. UMEGAKI and N. UCHIYAMA, J. Chem. Tech. Biotechnol. 32 (1982) 399.Google Scholar
  19. 19.
    Personal Communication with Dr. M. Stott, Queen’s University (2005).Google Scholar
  20. 20.
    PIETAK, D. SINDREY, M. SAYER and M.J. STOTT, in “The Bioactive Effects of Aqueous Silicate Introduced to Extracellular Media by Skelite Materials” (to be published).Google Scholar

Copyright information

© Springer Science + Business Media, Inc. 2006

Authors and Affiliations

  • L. Tuck
    • 1
  • M. Sayer
    • 1
  • M. Mackenzie
    • 2
  • J. Hadermann
    • 3
  • D. Dunfield
    • 1
  • A. Pietak
    • 1
  • J. W. Reid
    • 1
  • A. D. Stratilatov
    • 1
  1. 1.Department of PhysicsQueen’s UniversityKingston OntarioCanada
  2. 2.Department of Physics and AstronomyUniversity of GlasgowGlasgowUK
  3. 3.University of AntwerpAntwerpBelgium

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