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Interaction of pesticide pyroquilon with two different cucurbit[n]uril

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Journal of Inclusion Phenomena and Macrocyclic Chemistry Aims and scope Submit manuscript

Abstract

In this work, we report a conceptual strategy for preventing pesticide degradation using cucurbit[n]uril to encapsulate pyroquilon (Pyn). The host–guest inclusion complexes of pyroquilon (Pyn) with CB[7] and CB[8] were prepared and characterized using 1H NMR spectroscopy, quadrupole-time of flight mass spectrometry (Q-TOF), isothermal titration calorimetry (ITC) and UV absorbance spectrophotometry. The experimental results revealed that the entire Pyn molecule resides within the cavities of CB[7] and CB[8], forming 1:1 inclusion complexes between CB[n] and Pyn. Our study on the release of Pyn demonstrated that CB[n]@Pyn exhibit sustained- and slow-release properties. Moreover, CB[8] can effectively shield UV irradiation and thereby protect the Pyn from photodegradation. Therefore, CB[7]@Pyn and CB[8]@Pyn have great potential to be used as slow-release agents.

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Acknowledgements

We acknowledge the support of the “Chun Hui” Project of the Chinese Ministry of Education (No. Z2017001), the Creative Research Groups of Guizhou Provincial Education Department (2017-028), the Science and Technology Program of Guizhou Province (No. 20185781), and the Innovation Program for High-level Talents of Guizhou Province (No. 2016-5657).

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Authors and Affiliations

  1. State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering, Key Laboratory of Green Pesticide and Agricultural Bioengineering, Ministry of Education, Guizhou University, Guiyang, 550025, People’s Republic of China

    Ying Fan

  2. Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province, Guizhou University, Guiyang, 550025, People’s Republic of China

    Ying Fan, Ruihan Gao, Zhu Tao & Xin Xiao

  3. State Key Laboratory of Functions and Applications of Medicinal Plants, Guizhou Medical University, 3491 Baijin Road, Guiyang, 550014, People’s Republic of China

    Yangming Jiang

  4. College of Chemical and Environmental Engineering, Shandong University of Science and Technology, Qingdao, 266590, People’s Republic of China

    Bing Bian

  5. Commonwealth Scientific and Industrial Research Organization (CSIRO), Manufacturing, P.O. Box 218, Lindfield, NSW, 2070, Australia

    Gang Wei

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  1. Ying Fan
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  2. Ruihan Gao
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  5. Zhu Tao
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Correspondence to Zhu Tao, Gang Wei or Xin Xiao.

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Fan, Y., Gao, R., Jiang, Y. et al. Interaction of pesticide pyroquilon with two different cucurbit[n]uril. J Incl Phenom Macrocycl Chem 95, 207–213 (2019). https://doi.org/10.1007/s10847-019-00936-4

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