Microwave-assisted synthesis of 6-amino-β-cyclodextrins

  • Antonino Puglisi
  • John Spencer
  • James Clarke
  • John Milton
Short Communication

Abstract

A general microwave-assisted procedure for the synthesis of 6-amino-β-cyclodextrins is reported. Mono-tosyl-β-cyclodextrin was used as the starting material in a one-pot route employing a solvent-free microwave-assisted reaction with a liquid amine. Shorter reaction times were observed for the formation of 6-amino-β-cyclodextrins using this novel microwave approach compared to the thermal procedure.

Keywords

Microwave-assisted synthesis 6-amino-β-cyclodextrins Functionalised cyclodextrins Mono-pendant cyclodextrins 

Supplementary material

10847_2011_54_MOESM1_ESM.doc (1.1 mb)
Supplementary material 1 (DOC 1078 kb)

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Copyright information

© Springer Science+Business Media B.V. 2011

Authors and Affiliations

  • Antonino Puglisi
    • 1
  • John Spencer
    • 1
  • James Clarke
    • 2
  • John Milton
    • 2
  1. 1.School of ScienceUniversity of Greenwich at MedwayChathamUK
  2. 2.Oxford Nanopore Technologies LtdOxfordUK

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