Colorimetric recognition using functional phenolphthalein derivatives

Review Article
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Abstract

Three types of host molecules 1–3 based on a phenolphthalein (one of the most popular pH indicators) and two crown ethers were prepared for use in colorimetric recognition of linear diamines, triamines, sequence of non-protected dipeptides in methanol or water solution.

Keywords

Host–guest chemistry Molecular recognition Colorimetric recognition Phenolphthalein Protic solvent Hydrogen bonding 
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Notes

Acknowledgments

The author thanks all collaborators mentioned in the references. He especially thanks Prof. Kaoru Fuji and Prof. Takeo Kawabata for their suggestions and discussions, Dr. Daisuke Tanima, Dr. Tomokazu Kusumoto, Dr. Mohammad Nuruzzaman, Mr. Noriyuki Hayashi, and Ms. Yoko Imamura for their great contributions to this work. This study was partly supported by Grants-in-Aid for Scientific Research (Nos. 14572003 and 18390003) from the Ministry of Education, Culture, Sports, Science and Technology of Japan, and Foundation for Pharmaceutical Sciences, Japan. He also thanks Prof. Norihiro Tokitoh and Prof. Takahiro Sasamori (Kyoto Univ.) for performing the X-ray structural analysis, and Prof. Yasuhisa Kuroda (Kyoto Institute of Technology), Prof. Keiji Hirose and Prof. Yoshito Tobe (Osaka Univ.) for gifts of software for determination of binding constants. This is a paper selected for “HGCS Japan Award of Excellence 2007”.

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Copyright information

© Springer Science+Business Media B.V. 2008

Authors and Affiliations

  1. 1.Institute for Chemical ResearchKyoto UniversityUjiJapan

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