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First results and follow-up of a second-generation circular mapping and ablation catheter

  • Stefan Weber
  • Martin Höher
  • Dominik Schultes
Article

Abstract

Purpose

Pulmonary vein isolation with radiofrequency energy is widely used as a strategy for catheter ablation of atrial fibrillation (AF). Anatomically designed catheters have been developed to increase the efficiency of AF ablation procedures. The second-generation circular ablation catheter, PVAC GOLD, was re-designed to improve energy delivery and mitigate emboli. We investigated the procedural efficiency, biophysics, and chronic efficacy of PVAC GOLD in patients with AF.

Methods

We consecutively enrolled 40 patients (60 ± 11 years) with highly symptomatic, drug refractory AF. The first 20 patients were treated with the first-generation PVAC. The subsequent 20 patients were treated with the second-generation PVAC GOLD catheter. All patients were followed up at 3, 6, and 12 months.

Results

All 164 targeted PVs were successfully isolated. Ablations performed with PVAC GOLD showed a significant reduction in total number of ablations needed for PVI, fluoroscopy, and procedure times compared to PVAC (34.7 ± 7.0 vs. 27.0 ± 6.5; p = 0.009), fluoroscopy (29.5 ± 9.5 vs. 23.4 ± 7.0; p = 0.026), and procedure time (93.8 ± 18.9 vs. 83.1 ± 10.6; p = 0.033). PVAC GOLD showed improved biophysics including a reduction of low power ablations and an increase in mean effective energy delivery. At 12 months follow-up, AF recurrence rates were comparable in the two groups (35 vs. 30 %; p = 0.735). There were no adverse events.

Conclusions

The redesigned PVAC GOLD catheter demonstrates a reduction in radiofrequency ablation and procedure time and improved biophysics while maintaining chronic efficacy compared to the first-generation PVAC.

Keywords

Atrial fibrillation Catheter ablation Phased RF Multi-electrode ablation catheter 

Notes

Compliance with ethical standards

Written consent was obtained from all the patients, and the study protocol was approved by the institutional review board of Bayreuth Hospital.

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Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • Stefan Weber
    • 1
    • 2
  • Martin Höher
    • 1
  • Dominik Schultes
    • 1
  1. 1.Klinikum BayreuthDepartment of Cardiology and ElectrophysiologyBayreuthGermany
  2. 2.University of Regensburg and Praxis für Kardiologie und RhythmologieRegensburgGermany

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