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New drugs for atrial fibrillation

  • Matthias Hammwöhner
  • Jan Smid
  • Uwe Lendeckel
  • Andreas GoetteEmail author
Article

Abstract

Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia. Epidemiologic studies suggest that the number of patients with AF will triple in the next 30 years, and therefore, its impact on medical and economic issues will further increase. Due to the limited efficacy and significant side effects of antiarrhythmic drugs, much effort has been made to develop alternative pharmacologic treatments for AF. Novel approaches include new antiarrhythmic drugs and novel drug targets involved in molecular, proarrhythmogenic, atrial remodeling. Furthermore, novel anticoagulants are now clinically studied. This review briefly summarizes new developments in the pharmacotherapy for AF.

Keywords

Atrial fibrillation Therapy Drugs Pathophysiology Pharmacology 

Notes

Acknowledgements

This work is supported by the “Bundesministerium für Bildung und Forschung, Germany” (Kompetenznetz Vorhofflimmern, AF NET = the German Network of Competence in Atrial Fibrillation; Grant 01GI0204). Illustrations contain elements provided courtesy of Servier Medical Art.

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Copyright information

© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  • Matthias Hammwöhner
    • 1
  • Jan Smid
    • 1
  • Uwe Lendeckel
    • 2
  • Andreas Goette
    • 1
    Email author
  1. 1.Division of CardiologyUniversity Hospital MagdeburgMagdeburgGermany
  2. 2.Institute of Experimental Internal MedicineUniversity Hospital MagdeburgMagdeburgGermany

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