Generalized seizures in a neural field model with bursting dynamics
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Abstract
The mechanisms underlying generalized seizures are explored with neural field theory. A corticothalamic neural field model that has accounted for multiple brain activity phenomena and states is used to explore changes leading to pathological seizure states. It is found that absence seizures arise from instabilities in the system and replicate experimental studies in numerous animal models and clinical studies.
Keywords
Neural-field theory Corticothalamic Generalized seizuresNotes
Acknowledgments
This work was supported by the Australian Research Council Center of Excellence for Integrative Brain Function (ARC Grant CE140100007) and by ARC Grant FL1401000225.
Conflict of Interest
The authors declare that they have no conflict of interest.
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