Fragment-based drug discovery
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Keywords
Surface Plasmon Resonance High Throughput Screening Fluorescence Correlation Spectroscopy Fragment Library Ligand Efficiency
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.
Notes
Acknowledgments
I am grateful to Rod Hubbard of Vernalis and Mark Murko of Vertex for giving balanced answers to my many challenging questions and to David Bailey of IOTA Pharmaceuticals [22] for helping me with Table 1. I would also like to thank several people who have given me ideas but wished to remain anonymous.
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