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Journal of Assisted Reproduction and Genetics

, Volume 36, Issue 1, pp 139–143 | Cite as

Sub-endometrial contractility or computer-enhanced 3-D modeling scoring of the endometrium before embryo transfer: are they better than measuring endometrial thickness?

  • Nivin Samara
  • Robert F. Casper
  • Rawad Bassil
  • Mahvash Shere
  • Eran Barzilay
  • Raoul Orvieto
  • Jigal HaasEmail author
Assisted Reproduction Technologies
  • 64 Downloads

Abstract

Purpose

Recent studies have focused on transvaginal ultrasound measurement (TVUS) of sub-endometrial contractility and computer-enhanced 3-D modeling scoring of the endometrium prior to embryo transfer (ET).The aim of this study was to compare pregnancy outcome of patients who performed the 3-D scoring or the sub-endometrial measurement prior to the ET with patients that did not perform those procedures.

Methods

A single center retrospective cohort study of 635 freeze/thaw cycles of blastocysts vitrified on day 5 and transferred between January 2016 and August 2016.

Results

We compared the patients who performed 3-D scoring with the control group and found comparable patients’ characteristics, clinical pregnancy rates (42% vs. 44.3, p = NS, respectively), and ongoing pregnancy rates (31.7% vs. 33.9%, p = NS).We then compared the patients who performed the sub-endometrial wave measurements with the control group and found similar findings. The clinical pregnancy rate (38.2% vs. 44.3, p = NS, respectively) and the ongoing pregnancy rate (30.8% vs. 33.9%) were comparable between the two groups. We performed a regression analysis to examine the independent contribution of different variables to the ongoing pregnancy rates. Both the 3-D and the wave count procedures were not found to have any influence on the ongoing pregnancy rates.

Conclusions

Although new ultrasonic methods of evaluating the endometrium have been proposed during the last years, these methods have not been shown to improve the pregnancy rates compared to the original method of assessing the endometrium by measuring the endometrial thickness.

Keywords

Sub-endometrial waves 3-D endometrial scoring FET 

Notes

Compliance with ethical standards

Ethics statement

The study was approved by the Research Ethics Board at Mount Sinai Hospital in Toronto.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • Nivin Samara
    • 1
    • 2
  • Robert F. Casper
    • 1
    • 3
  • Rawad Bassil
    • 1
  • Mahvash Shere
    • 1
  • Eran Barzilay
    • 4
  • Raoul Orvieto
    • 4
    • 5
  • Jigal Haas
    • 1
    • 4
    Email author
  1. 1.TRIO fertility partnersTorontoCanada
  2. 2.The Fertility InstituteLis Maternity Hospital, Sourasky Medical CenterTel- AvivIsrael
  3. 3.Division of Reproductive SciencesUniversity of Toronto, Lunenfeld-Tanenbaum Research Institute, Mount Sinai HospitalTorontoCanada
  4. 4.Infertility and IVF Unit, Department of Obstetrics and GynecologyChaim Sheba Medical Center (Tel Hashomer), Tel -Aviv UniversityRamat GanIsrael
  5. 5.Tarnesby-Tarnowski Chair for Family Planning and Fertility Regulation, Sackler Faculty of MedicineTel-Aviv UniversityTel Aviv-YafoIsrael

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