A small field for fertile science: the low visibility of reproductive science in high impact journals

  • Francesca E. Duncan
  • Benjamin Derman
  • Teresa K. Woodruff
Opinion

Abstract

Purpose

Our success as a field and as individuals in reproductive science and medicine relies on our ability to produce high quality work that has broad visibility and impact. A common metric for assessing such success is the quantity of publications that are published in journals with high impact factors. It is unclear, however, how frequently work related to reproductive science and medicine actually appears in what are considered the highest impact journals.

Methods

To address this gap in knowledge, we first determined how the field of reproductive biology in general compared to other research areas in terms of composite journal impact factor. Second, using a targeted search approach in the PubMed database, we examined the relationship between a journal’s impact factor and the number of reproductive research articles published per journal issue.

Results

We found that compared to other major scientific disciplines, our field lacks journals with impact factors above 4. In addition, primary original research articles on reproduction—irrespective of male or female search terms—do not appear often in high impact journals. Instead, there is an increased percentage of secondary reproductive literature in high impact journals compared to topic-specific journals of lower impact.

Conclusions

There are likely several explanations for why reproductive science and medicine has low visibility, including the field’s small relative size, its lack of a specific disease and associated strong advocacy, and its surrounding social, ethical, and political unease. Nevertheless, there are concrete actions we can take to minimize the role of impact factor in our evaluation while simultaneously increasing influence through global awareness of the importance and need for reproductive research.

Keywords

Reproduction Impact factor Male Female Gamete Gonad Ovary Testis Mammalian 

References

  1. 1.
    Edwards RG. The bumpy road to human in vitro fertilization. Nat Med. 2001;7(10):1091–4. doi:10.1038/nm1001-1091.PubMedCrossRefGoogle Scholar
  2. 2.
    Pincus G, Baum OS. On the interaction of oestrin and the ovary stiumulating principles of extracts of the urine of pregnancy. Am J Physiol. 1932;102:241–8.Google Scholar
  3. 3.
    Pincus G, Chang MC. The effects of progesterone and related compounds on ovulation and early development in the rabbit. Acta Physiol Latinoam. 1953;3:117–83.Google Scholar
  4. 4.
    Pincus G, Chang MC, Hafez ES, Zarrow MX, Merrill A. Effects of certain 19-nor steroids on reproductive processes in animals. Science. 1956;124:890–1.PubMedCrossRefGoogle Scholar
  5. 5.
    Chang MC, Hafez ES, Merrill A, Pincus G, Zarrow MX. Studies of the biological activity of certain 19-nor steroids in female animals. Endocrinology. 1956;59(6):695–707.PubMedGoogle Scholar
  6. 6.
    Pincus G. Some effects of progesterone and related compounds upon reproduction and early development in mammals. Acta Endocrinol Suppl (Copenh). 1956;23 Suppl 28:18–36.Google Scholar
  7. 7.
    Ingle DJ. Gregory Goodwin Pincus, April 9, 1903–August 22, 1967. Biogr Mem Natl Acad Sci. 1971;42:229–70.PubMedGoogle Scholar
  8. 8.
    Rock J, Menkin MF. In vitro fertilization and cleavage of human ovarian eggs. Science. 1944;100(2588):105–7. doi:10.1126/science.100.2588.105.PubMedCrossRefGoogle Scholar
  9. 9.
    Edwards RG. The experimental induction of gynogenesis in the mouse. I. Irradiation of the sperm by x-rays. Proc R Soc Lond B Containing Papers Biol Character R Soc. 1957;146(925):469–87.CrossRefGoogle Scholar
  10. 10.
    Donini P, Puzzuoli D, Montezemolo R. Purification of gonadotrophin from human menopausal urine. Acta Endocrinol (Copenh). 1964;45:321–8.Google Scholar
  11. 11.
    Edwards RG. Maturation in vitro of human ovarian oocytes. Lancet. 1965;2(7419):926–9.PubMedCrossRefGoogle Scholar
  12. 12.
    Edwards RG. Maturation in vitro of mouse, sheep, cow, pig, rhesus monkey and human ovarian oocytes. Nature. 1965;208(5008):349–51.PubMedCrossRefGoogle Scholar
  13. 13.
    Edwards RG, Steptoe PC, Purdy JM. Establishing full-term human pregnancies using cleaving embryos grown in vitro. Br J Obstet Gynaecol. 1980;87(9):737–56.PubMedCrossRefGoogle Scholar
  14. 14.
    Vogel G, Enserink M. Nobel prizes. Honor for test tube baby pioneer. Science. 2010;330(6001):158–9. doi:10.1126/science.330.6001.158.PubMedCrossRefGoogle Scholar
  15. 15.
    Fisher SJ, Giudice LC. Retrospective. Robert G. Edwards (1925–2013). Science. 2013;340(6134):825.PubMedCrossRefGoogle Scholar
  16. 16.
    Smith R. Commentary: the power of the unrelenting impact factor–is it a force for good or harm? Int J Epidemiol. 2006;35(5):1129–30. doi:10.1093/ije/dyl191.PubMedCrossRefGoogle Scholar
  17. 17.
    Garfield E. Citation indexes for science; a new dimension in documentation through association of ideas. Science. 1955;122(3159):108–11.PubMedCrossRefGoogle Scholar
  18. 18.
    Garfield E. Citation analysis as a tool in journal evaluation. Science. 1972;178(4060):471–9.PubMedCrossRefGoogle Scholar
  19. 19.
    Garfield E. The history and meaning of the journal impact factor. JAMA. 2006;295(1):90–3. doi:10.1001/jama.295.1.90.PubMedCrossRefGoogle Scholar
  20. 20.
    Misteli T. Eliminating the impact of the impact factor. J Cell Biol. 2013;201(5):651–2. doi:10.1083/jcb.201304162.PubMedCentralPubMedCrossRefGoogle Scholar
  21. 21.
    Walker RL, Sykes L, Hemmelgarn BR, Quan H. Authors’ opinions on publication in relation to annual performance assessment. BMC Med Educ. 2010;10:21. doi:10.1186/1472-6920-10-21.PubMedCentralPubMedCrossRefGoogle Scholar
  22. 22.
    Franzoni C, Scellato G, Stephan P. Science policy. Changing incentives to publish. Science. 2011;333(6043):702–3. doi:10.1126/science.1197286.PubMedCrossRefGoogle Scholar
  23. 23.
    Gleicher N. Strategies to improve insurance coverage for infertility services. Fertil Steril. 1998;70(6):1006–8.PubMedCrossRefGoogle Scholar
  24. 24.
    Hammoud AO, Gibson M, Stanford J, White G, Carrell DT, Peterson M. In vitro fertilization availability and utilization in the United States: a study of demographic, social, and economic factors. Fertil Steril. 2009;91(5):1630–5. doi:10.1016/j.fertnstert.2007.10.038.PubMedCrossRefGoogle Scholar
  25. 25.
    Jain T, Harlow BL, Hornstein MD. Insurance coverage and outcomes of in vitro fertilization. N Engl J Med. 2002;347(9):661–6. doi:10.1056/NEJMsa013491.PubMedCrossRefGoogle Scholar
  26. 26.
    Campo-Engelstein L. For the sake of consistency and fairness: why insurance companies should cover fertility preservation treatment for iatrogenic infertility. Cancer Treat Res. 2010;156:381–8. doi:10.1007/978-1-4419-6518-9_29.PubMedCentralPubMedCrossRefGoogle Scholar
  27. 27.
    Brouillet M, Turner L. Bioethics, religion, and democratic deliberation: policy formation and embryonic stem cell research. HEC Forum Interdisc J Hosp Ethical Leg Issues. 2005;17(1):49–63.Google Scholar
  28. 28.
    Dolin G, Roberts DE, Rodriguez LM, Woodruff TK. Medical hope, legal pitfalls: potential legal issues in the emerging field of oncofertility. Cancer Treat Res. 2010;156:111–34. doi:10.1007/978-1-4419-6518-9_9.PubMedCentralPubMedCrossRefGoogle Scholar
  29. 29.
    Kastenberg ZJ, Odorico JS. Alternative sources of pluripotency: science, ethics, and stem cells. Transplant Rev. 2008;22(3):215–22. doi:10.1016/j.trre.2008.04.002.CrossRefGoogle Scholar
  30. 30.
    Woodruff TK, Zoloth L, Campo-Engelstein L, Rodriguez S. Oncofertility: ethical, legal, social, and medical perspectives. Preface. Cancer Treat Res. 2010;156:v–vii.PubMedGoogle Scholar
  31. 31.
    Zoloth L, Backhus L, Woodruff T. Waiting to be born: the ethical implications of the generation of “NUBorn” and “NUAge” mice from pre-pubertal ovarian tissue. Am J Bioeth. 2008;8(6):21–9. doi:10.1080/15265160802248203.PubMedCentralPubMedCrossRefGoogle Scholar
  32. 32.
    Yoshimura Y. Bioethical aspects of regenerative and reproductive medicine. Hum Cell. 2006;19(2):83–6. doi:10.1111/j.1749-0774.2006.00009.x.PubMedCrossRefGoogle Scholar
  33. 33.
    Shanner L, Nisker J. Bioethics for clinicians: 26. Assisted reproductive technologies. Can Med Assoc J. 2001;164(11):1589–94.Google Scholar
  34. 34.
    Campo-Engelstein L, Rodriguez S, Tingen C, Woodruff T. Practical parthenote policy and the practice of science. Am J Bioeth. 2011;11(3):W1–2. doi:10.1080/15265161.2011.563162.PubMedCrossRefGoogle Scholar
  35. 35.
    Rodriguez S, Campo-Engelstein L, Tingen C, Woodruff T. An obscure rider obstructing science: the conflation of parthenotes with embryos in the Dickey-Wicker amendment. Am J Bioeth. 2011;11(3):20–8. doi:10.1080/15265161.2010.546472.PubMedCrossRefGoogle Scholar
  36. 36.
    Tingen C, Rodriguez S, Campo-Engelstein L, Woodruff TK. Research funding. Politics and parthenotes. Science. 2010;330(6003):453. doi:10.1126/science.1196881.PubMedCrossRefGoogle Scholar
  37. 37.
    Schutte HK, Svec JG. Reaction of Folia Phoniatrica et Logopaedica on the current trend of impact factor measures. Folia Phoniatr Logop Off Organ Int Assoc Logopedics Phoniatrics. 2007;59(6):281–5. doi:10.1159/000108334.CrossRefGoogle Scholar
  38. 38.
    Opatrny T. Playing the system to give low-impact journal more clout. Nature. 2008;455(7210):167. doi:10.1038/455167b.PubMedCrossRefGoogle Scholar
  39. 39.
    Fersht A. The most influential journals: impact factor and Eigenfactor. Proc Natl Acad Sci U S A. 2009;106(17):6883–4. doi:10.1073/pnas.0903307106.PubMedCentralPubMedCrossRefGoogle Scholar
  40. 40.
    Rizkallah J, Sin DD. Integrative approach to quality assessment of medical journals using impact factor, eigenfactor, and article influence scores. PloS One. 2010;5(4):e10204. doi:10.1371/journal.pone.0010204.PubMedCentralPubMedCrossRefGoogle Scholar
  41. 41.
    Albert KM. Open access: implications for scholarly publishing and medical libraries. J Med Libr Assoc. 2006;94(3):253–62.PubMedCentralPubMedGoogle Scholar
  42. 42.
    Roberts RG, Alfred J. Collection overview: ten years of wonderful open access science. PLoS Biol. 2013;11(10):e1001688. doi:10.1371/journal.pbio.1001688.PubMedCentralPubMedCrossRefGoogle Scholar
  43. 43.
    Bjork BC, Solomon D. Open access versus subscription journals: a comparison of scientific impact. BMC Med. 2012;10:73. doi:10.1186/1741-7015-10-73.PubMedCentralPubMedCrossRefGoogle Scholar
  44. 44.
    Bohannon J. Who’s afraid of peer review? Science. 2013;342(6154):60–5. doi:10.1126/science.342.6154.60.PubMedCrossRefGoogle Scholar
  45. 45.
    Pion GM, McClure ME, Fazleabas AT. Outcomes of an intensive summer course in reproductive biology. Biol Reprod. 2006;74(2):230–5. doi:10.1095/biolreprod.105.045427.PubMedCrossRefGoogle Scholar
  46. 46.
    Faurot M, Woodruff TK. The oncofertility saturday academy: a paradigm to expand the educational opportunities and ambitions of high school girls. Cancer Treat Res. 2010;156:321–44. doi:10.1007/978-1-4419-6518-9_25.PubMedCentralPubMedCrossRefGoogle Scholar
  47. 47.
    Smeyers C, Wallach H, Woodruff TK. Repropedia: a reproductive lexicon to fill the gap in reproductive terminology. Biol Reprod. 2012;87(4):98. doi:10.1095/biolreprod.112.104000.PubMedCentralPubMedCrossRefGoogle Scholar
  48. 48.
    Wuchty S, Jones BF, Uzzi B. The increasing dominance of teams in production of knowledge. Science. 2007;316(5827):1036–9. doi:10.1126/science.1136099.PubMedCrossRefGoogle Scholar
  49. 49.
    Uzzi B, Mukherjee S, Stringer M, Jones B. Atypical combinations and scientific impact. Science. 2013;342(6157):468–72. doi:10.1126/science.1240474.PubMedCrossRefGoogle Scholar
  50. 50.
    Jones BF, Wuchty S, Uzzi B. Multi-university research teams: shifting impact, geography, and stratification in science. Science. 2008;322(5905):1259–62. doi:10.1126/science.1158357.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Francesca E. Duncan
    • 1
  • Benjamin Derman
    • 1
  • Teresa K. Woodruff
    • 1
  1. 1.Department of Obstetrics and Gynecology, Feinberg School of MedicineNorthwestern UniversityChicagoUSA

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