Clinical outcomes of elective single morula embryo transfer versus elective single blastocyst embryo transfer in IVF-ET

  • Sang Min Kang
  • Sang Won Lee
  • Hak Jun Jeong
  • San Hyun Yoon
  • Min Whan Koh
  • Jin Ho Lim
  • Seong Goo Lee
ASSISTED REPRODUCTION TECHNOLOGIES

Abstract

Purpose

To compare the clinical outcomes of elective single morula embryo transfer (eSMET) versus elective single blastocyst embryo transfer (eSBET) in selected patients.

Methods

This study was a retrospective study which analyzed for 271 cycles in women under 37 years of age who are undergoing their first or second trial of in vitro fertilization-embryo transfer (IVF-ET) from January 2008 to December 2009. The eSMET was performed on day 4 (n = 130) and the eSBET was conducted on day 5 (n = 141).

Results

The clinical pregnancy rate (51.5% vs. 51.8%, p = 0.97), implantation rate (52.3% vs. 52.5%, p = 0.98), and live birth rate (39.2% vs. 44.7%, p = 0.36) were similar in the eSMET and eSBET groups, respectively. The miscarriage rate of the eSMET group (23.9%) was slightly higher than that of the eSBET group (13.7%) (p = 0.12), without reaching statistical significance. There was only one case of monozygotic twin pregnancy in each group.

Conclusions

The clinical outcomes of day 4 eSMET were comparable to those of day 5 eSBET. Therefore, day 4 eSMET is a viable option or an alternative to day 5 eSBET, with no difference in success rates.

Keywords

Elective single embryo transfer Morula Blastocyst Monozygotic twins Live birth 

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Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Sang Min Kang
    • 1
  • Sang Won Lee
    • 1
  • Hak Jun Jeong
    • 1
  • San Hyun Yoon
    • 2
  • Min Whan Koh
    • 3
  • Jin Ho Lim
    • 2
  • Seong Goo Lee
    • 1
  1. 1.Maria Fertility ClinicDaeguRepublic of Korea
  2. 2.Seoul Maria Fertility HospitalSeoulRepublic of Korea
  3. 3.Department of Obstetrics and Gynecology, College of MedicineYeungnam UniversityDaeguRepublic of Korea

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