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Use of microalgae: Tetraselmis tetrathele extract in formulation of nanoemulsions for cosmeceutical application

  • A. W. Farahin
  • F. M. YusoffEmail author
  • M. Basri
  • N. Nagao
  • M. Shariff
Article

Abstract

Cosmeceuticals are cosmetic-hybrids intended to enhance health and beauty of the skin. Topical delivery of antioxidants from natural bioresources has gained attention in line with the increasing demand for harmless cosmetics. Tetraselmis tetrathele is a microalgae species, which has high antioxidant contents. In this work, ternary phase analysis with different compositions of oil, surfactant, and water was conducted to evaluate homogeneity and stability of nanoemulsion lotion containing 1% T. tetrathele extract. The three formulations T1, T2, and T3 containing various percentages of the surfactant Tween 80, T1 (20 wt% of Tween 80), T2 (15 wt% of Tween 80), and T3 (10 wt% of Tween 80), were analyzed for size and zeta potential to evaluate stability of the nanoemulsion. All particles were nanosized ranging from 102.3 to 249.5 nm. Zeta potential analysis for all emulsions showed negative values from − 33.2 to − 71.7 mV, which indicates high stability of the nanoemulsion. In order to evaluate the storage stability, a stability test was conducted at different temperature levels (4, 25, and 45 °C) for 10 weeks. At all temperature conditions, T1, T2, and T3 were stable with exception of T3 that precipitated and sedimented after 8 weeks. This study illustrated that T. tetrathele extract can be used as bioactive compound for nanocosmeceutical products, which has high homogeneity and stability.

Keywords

Topical nanoemulsions Microalgae Tetraselmis tetrathele extract 

Notes

Funding information

This project was funded by the Ministry of Higher Education Malaysia (MOHE) through a Project on the Higher Institution Centre of Excellence (HICoE) awarded to the Institute of Bioscience, Universiti Putra Malaysia, SATREPS-COSMOS Project, and the Ministry of Science, Technology, and Innovation Malaysia (MOSTI) through eScience, Project No. 04-01-04-SF1012.

Supplementary material

10811_2018_1694_MOESM1_ESM.docx (24 kb)
ESM 1 (DOCX 23 kb)

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Copyright information

© Springer Nature B.V. 2018

Authors and Affiliations

  • A. W. Farahin
    • 1
  • F. M. Yusoff
    • 1
    • 2
    Email author
  • M. Basri
    • 3
  • N. Nagao
    • 1
  • M. Shariff
    • 4
  1. 1.Laboratory of Marine Biotechnology, Institute of BioscienceUniversiti Putra MalaysiaSerdangMalaysia
  2. 2.Department of Aquaculture, Faculty of AgricultureUniversiti Putra MalaysiaSerdangMalaysia
  3. 3.Department of Chemistry, Faculty of ScienceUniversiti Putra MalaysiaSerdangMalaysia
  4. 4.Department of Veterinary Clinical Studies, Faculty of Veterinary MedicinesUniversiti Putra MalaysiaSerdangMalaysia

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