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Journal of Autism and Developmental Disorders

, Volume 47, Issue 11, pp 3370–3379 | Cite as

Diagnosing ASD in Adults Without ID: Accuracy of the ADOS-2 and the ADI-R

  • Laura Fusar-PoliEmail author
  • Natascia Brondino
  • Matteo Rocchetti
  • Cristina Panisi
  • Umberto Provenzani
  • Stefano Damiani
  • Pierluigi Politi
Original Paper

Abstract

Diagnosing autism spectrum disorder (ASD) in adulthood often represents a challenge in clinical practice. The aim of the present study was to evaluate the sensitivity and specificity of the ADOS and ADI-R in diagnosing ASD in adults. 113 subjects with an IQ of 70 or above were assessed through an extensive clinical evaluation. The ADOS-2 Module 4 and the ADI-R were separately administered by staff members blind to clinical judgment. Our results cautiously confirm the accuracy of ADOS-2 Module 4, while suggest that ADI-R might not be reliable in adults without intellectual disability. Clinicians’ training and experience remains of primary importance while assessing adults who could potentially belong to the autism spectrum.

Keywords

Autism Adult DSM-5 Diagnosis ADOS ADI-R 

Notes

Acknowledgments

This research received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors. The authors would like to thank all the patients of Laboratorio Autismo and their families.

Author Contributions

LF and NB conceived of the study, participated in its design and coordination, performed the evaluations, analyzed the data, and drafted the manuscript; MR and CP participated in the design and interpretation of the data, performed the evaluations, and helped to draft the manuscript; UP and SD participated in the interpretation of the data and helped to write the manuscript; PP conceived of the study, participated in its design and coordination, performed the evaluations, and helped to draft the manuscript. All authors read and approved the final manuscript.

Compliance with Ethical Standards

Conflict of interest

All authors declare that they have no conflict of interest.

Ethical Approval

The authors assert that all procedures contributing to this work comply with the ethical standards of the relevant national and institutional committees on human experimentation and with the Helsinki Declaration of 1975, as revised in 2008.

Informed Consent

Informed consent was obtained from all individuals included in this study.

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Copyright information

© Springer Science+Business Media, LLC 2017

Authors and Affiliations

  1. 1.Department of Brain and Behavioral SciencesUniversity of PaviaPaviaItaly

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