Screening for Autism with the SRS and SCQ: Variations across Demographic, Developmental and Behavioral Factors in Preschool Children
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The Social Communication Questionnaire (SCQ) and the Social Responsiveness Scales (SRS) are commonly used screeners for autism spectrum disorder (ASD). Data from the Study to Explore Early Development were used to examine variations in the performance of these instruments by child characteristics and family demographics. For both instruments, specificity decreased as maternal education and family income decreased. Specificity was decreased with lower developmental functioning and higher behavior problems. This suggests that the false positive rates of the SRS and the SCQ are associated with child characteristics and family demographic factors. There is a need for ASD screeners that perform well across socioeconomic and child characteristics. Clinicians should be mindful of differential performance of these instruments in various groups of children.
KeywordsAutism Screener Demographics Maternal education Development
This research is supported by the Centers for Disease Control and Prevention, Centers for Autism and Developmental Disabilities Research, Study to Explore Early Development through six cooperative agreements: Cooperative Agreement Number U10DD000180, Colorado Department of Public Health/University of Colorado School of Medicine; Cooperative Agreement Number U10DD000181, Kaiser Foundation Research Institute (CA); Cooperative Agreement Number U10DD000182, University of Pennsylvania; Cooperative Agreement Number U10DD000183, Johns Hopkins University; Cooperative Agreement Number U10DD000184, University of North Carolina at Chapel Hill; and Cooperative Agreement Number U10DD000498, Michigan State University. Additional support came in part from core grants awarded to JFK Partners, the University Center for Excellence in Developmental Disabilities at the University Colorado School of Medicine from the U.S. Department of Health and Human Services, through the Administration on Developmental Disabilities Grant #90DD0561.
EJM developed the analysis idea, coordinated analysis and writing activities, oversaw development of the manuscript. NR conducted literature reviews, participated in writing and conceptual development of the analysis. CL conducted the analyses, and contributed to writing the manuscript. LW participated in the design of the analysis, oversaw data collection from one of the sites and contributed to the writing of the manuscript. CD participated in the design of the analysis, oversaw data collection from one of the sites and contributed to the writing of the manuscript. AA contributed to the initial design of the analysis, and contributed to the writing of the manuscript. SJ contributed to the initial design of the analysis, and contributed to the writing of the manuscript. LL participated in the design of the analysis and contributed to the writing of the manuscript. SEL participated in the design of the analysis and contributed to the writing of the manuscript. SAR participated in the design of the analysis and contributed to the writing of the manuscript. All authors read and approved the final manuscript.
Compliance with Ethical Standards
All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. Each participating site (California, Colorado, Georgia, Maryland, North Carolina & Pennsylvania) each obtained Institutional Review Board approval separately from their home institutions before any data were collected.
- Autism and Developmental Disabilities Monitoring Network (2016). Retrieved from http://www.cdc.gov/ncbddd/autism/addm.html.
- Achenbach, T. M., & Rescorla, L. A. (2001). Manual for the ASEBA school-age forms & profiles. Burlington, VT: University of Vermont, Research Center for Children, Youth, & Families.Google Scholar
- Bölte, S., Westerwald, E., Holtmann, M., Freitag, C., & Poustka, F. (2011). Autistic traits and autism spectrum disorders: The clinical validity of two measures presuming a continuum of social communication skills. Journal of Autism and Developmental Disorders, 41(1), 66–72. doi: 10.1007/s10803-010-1024-9.CrossRefPubMedGoogle Scholar
- Constantino, J., & Gruber, C. (2005). Social responsiveness scale. Los Angeles: CA: Western Psychological Services.Google Scholar
- Constantino, J. N. (2002). The social responsiveness scale. Los Angeles, CA: Western Psychological Services.Google Scholar
- Constantino, J. N., Davis, S. A., Todd, R. D., Schindler, M. K., Gross, M. M., Brophy, S. L., … Reich, W. (2003a). Validation of a brief quantitative measure of autistic traits: Comparison of the Social Responsiveness Scale with the Autism Diagnostic Interview-Revised. Journal of Autism and Developmental Disorders, 33(4), 427–433.CrossRefPubMedGoogle Scholar
- Constantino, J. N., Hudziak, J. J., & Todd, R. D. (2003b). Deficits in reciprocal social behavior in male twins: Evidence for a genetically independent domain of psychopathology. Journal of the American Academy of Child & Adolescent Psychiatry, 42(4), 458–467. doi: 10.1097/01.CHI.0000046811.95464.21.CrossRefGoogle Scholar
- DiGuiseppi, C. G., Daniels, J. L., Fallin, D. M., Rosenberg, S. A., Schieve, L. A., Thomas, K. C., … Schendel, D. E. (2016). Demographic profile of families and children enrolled in the Study to Explore Early Development (SEED): A case-control study of autism spectrum disorder. Disability Health Journal, 64, 332–341.Google Scholar
- Frazier, T. W., Ratliff, K. R., Gruber, C., Zhang, Y., Law, P. A., & Constantino, J. N. (2014). Confirmatory factor analytic structure and measurement invariance of quantitative autistic traits measured by the Social Responsiveness Scale-2. Autism: The International Journal of Research and Practice, 8(1), 31–44. doi: 10.1177/1362361313500382.CrossRefGoogle Scholar
- Lord, C., Risi, S., Lambrecht, L., Cook, E. H. Jr., Leventhal, B. L., DiLavore, P. C., … Rutter, M. (2000). The Autism Diagnostic Observation Schedule-Generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism & Developmental Disorders, 30(3), 205–223.CrossRefGoogle Scholar
- Mullen, E. M. (1995). Mullen scales of early learning (pp. 58–64). Circle Pines, MN: AGS.Google Scholar
- Oosterling, I., Rommelse, N., de Jonge, M., van der Gaag, R. J., Swinkels, S., Roos, S., … Buitelaar, J. (2010a). How useful is the Social Communication Questionnaire in toddlers at risk of autism spectrum disorder? Journal of Child Psychology and Psychiatry, 51(11), 1260–1268. doi: 10.1111/j.1469-7610.2010.02246.x.CrossRefPubMedGoogle Scholar
- Oosterling, I. J., Wensing, M., Swinkels, S. H., Van Der Gaag, R. J., Visser, J. C., Woudenberg, T., … Buitelaar, J. K. (2010b). Advancing early detection of autism spectrum disorder by applying an integrated two-stage screening approach. Journal of Child Psychology and Psychiatry, 51(3), 250–258.CrossRefPubMedGoogle Scholar
- Peters-Scheffer, N., Didden, R., Korzilius, H., & Matson, J. (2012). Cost comparison of early intensive behavioral intervention and treatment as usual for children with autism spectrum disorder in the Netherlands. Research in Developmental Disabilities, 33(6), 1763–1772. doi: 10.1016/j.ridd.2012.04.006.CrossRefPubMedGoogle Scholar
- Rutter, M., Bailey, A., & Lord, C. (2003). Social communication questionnaire. Los Angeles, CA: Western Psychological Services.Google Scholar
- Scarpa, A., Reyes, N. M., Patriquin, M. A., Lorenzi, J., Hassenfeldt, T. A., Desai, V. J., & Kerkering, K. W. (2013). The modified checklist for autism in toddlers: Reliability in a diverse rural american sample. Journal of Autism and Developmental Disorders, 43(10), 2269–2279. doi: 10.1007/s10803-013-1779-x.CrossRefPubMedGoogle Scholar
- Schanding, G. T. Jr., Nowell, K. P., & Goin-Kochel, R. P. (2012). Utility of the social communication questionnaire-current and social responsiveness scale as teacher-report screening tools for autism spectrum disorders. Journal of Autism and Developmental Disorders, 42(8), 1705–1716. doi: 10.1007/s10803-011-1412-9.CrossRefPubMedGoogle Scholar
- Schendel, D., DiGuiseppi, C., Croen, L., Fallin, M. D., Reed, P., Schieve, L., … Yeargin-Allsopp, M. (2012). The Study to Explore Early Development (SEED): A Multisite Epidemiologic Study of Autism by the Centers for Autism and Developmental Disabilities Research and Epidemiology (CADDRE) Network. Journal of Autism and Developmental Disorders, 42(10), 2121–2140. doi: 10.1007/s10803-012-1461-8.CrossRefPubMedPubMedCentralGoogle Scholar
- Snow, A. V., & Lecavalier, L. (2008). Sensitivity and specificity of the Modified Checklist for Autism in Toddlers and the Social Communication Questionnaire in preschoolers suspected of having pervasive developmental disorders. Autism: The International Journal of Research and Practice, 12(6), 627–644. doi: 10.1177/1362361308097116.CrossRefGoogle Scholar
- Sparrow, S. S., Balla, D. A., & Cicchetti, D. (2005). Vineland adaptive behavior scales. Circle Pines, MN: American Guidance Service.Google Scholar
- The OSU Research Unit on Pediatric Psychopharmacology (2005). OSU Autism Rating Scale-DSM-IV (OARS; Adapted for SEED). Retrieved from http://psychmed.osu.edu/resources.htm.
- Wiggins, L. D., Barger, B., Moody, E., Soke, G., Pandey, J., & Levy, S. (2017). Brief report: The ados calibrated severity score best measures autism diagnostic symptom severity in pre-school children. Journal of Autism and Developmental Disorders. doi: 10.1007/s10803-017-3072-x 28265795.PubMedCentralGoogle Scholar
- Wiggins, L. D., Reynolds, A., Rice, C. E., Moody, E. J., Bernal, P., Blaskey, L., ... Levy, S. E. (2015). Using standardized diagnostic instruments to classify children with autism in the study to explore early development. Journal of Autism and Developmental Disorders, 45(5), 1271–1280.CrossRefPubMedPubMedCentralGoogle Scholar