Journal of Autism and Developmental Disorders

, Volume 46, Issue 8, pp 2797–2805 | Cite as

Brief Report: Cognitive Control of Social and Nonsocial Visual Attention in Autism

  • Antoinette Sabatino DiCriscio
  • Stephanie J. Miller
  • Eleanor K. Hanna
  • Megan Kovac
  • Lauren Turner-Brown
  • Noah J. Sasson
  • Jeffrey Sapyta
  • Vanessa Troiani
  • Gabriel S. Dichter
Brief Report

Abstract

Prosaccade and antisaccade errors in the context of social and nonsocial stimuli were investigated in youth with autism spectrum disorder (ASD; n = 19) a matched control sample (n = 19), and a small sample of youth with obsessive compulsive disorder (n = 9). Groups did not differ in error rates in the prosaccade condition for any stimulus category. In the antisaccade condition, the ASD group demonstrated more errors than the control group for nonsocial stimuli related to circumscribed interests, but not for other nonsocial stimuli or for social stimuli. Additionally, antisaccade error rates were predictive of core ASD symptom severity. Results indicate that the cognitive control of visual attention in ASD is impaired specifically in the context of nonsocial stimuli related to circumscribed interests.

Keywords

Autism spectrum disorder Visual attention Cognitive control Eyetracking 

References

  1. Agam, Y., Joseph, R. M., Barton, J. J. S., & Manoach, D. S. (2010). Reduced cognitive control of response inhibition by the anterior cingulate cortex in autism spectrum disorders. NeuroImage, 52(1), 336–347. doi:10.1016/j.neuroimage.2010.04.010.CrossRefPubMedPubMedCentralGoogle Scholar
  2. Boraston, Z., & Blakemore, S.-J. (2007). The application of eye-tracking technology in the study of autism. The Journal of Physiology, 581(3), 893–898. doi:10.1113/jphysiol.2007.133587.CrossRefPubMedPubMedCentralGoogle Scholar
  3. Boyd, B. A., Conroy, M. A., Mancil, G. R., Nakao, T., & Alter, P. J. (2007). Effects of circumscribed interests on the social behaviors of children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 37(8), 1550–1561.CrossRefPubMedGoogle Scholar
  4. Chawarska, K., Klin, A., Paul, R., Macari, S., & Volkmar, F. (2009). A prospective study of toddlers with ASD: Short-term diagnostic and cognitive outcomes. Journal of Child Psychology and Psychiatry, 50(10), 1235–1245. doi:10.1111/j.1469-7610.2009.02101.x.CrossRefPubMedPubMedCentralGoogle Scholar
  5. Constantino, J. N., & Gruber, C. P. (2002). The Social Responsiveness Scale. Los Angeles: Western Psychological Services.Google Scholar
  6. Cuthbert, B. N., & Insel, T. R. (2013). Toward the future of psychiatric diagnosis: The seven pillars of RDoC. BMC Medicine, 11, 126.CrossRefPubMedPubMedCentralGoogle Scholar
  7. Dichter, G. S., Felder, J. N., & Bodfish, J. W. (2009). Autism is characterized by dorsal anterior cingulate hyperactivation during social target detection. Social Cognitive and Affective Neuroscience. doi:10.1093/scan/nsp017.PubMedCentralGoogle Scholar
  8. Dichter, G. S., Felder, J. N., Green, S. R., Rittenberg, A. M., Sasson, N. J., & Bodfish, J. W. (2012). Reward circuitry function in autism spectrum disorders. Social Cognitive and Affective Neuroscience, 7, 160–172. doi:10.1093/scan/nsq095.CrossRefPubMedGoogle Scholar
  9. Fletcher-Watson, S., Leekam, S. R., Benson, V., Frank, M. C., & Findlay, J. M. (2009). Eye-movements reveal attention to social information in autism spectrum disorder. Neuropsychologia, 47(1), 248–257. doi:10.1016/j.neuropsychologia.2008.07.016.CrossRefPubMedGoogle Scholar
  10. Gotham, K., Risi, S., Dawson, G., Tager-Flusberg, H., Joseph, R., Carter, A., et al. (2008). A replication of the Autism Diagnostic Observation Schedule (ADOS) revised algorithms. Journal of the American Academy of Child & Adolescent Psychiatry, 47(6), 642–651.CrossRefGoogle Scholar
  11. Grelotti, D. J., Klin, A. J., Gauthier, I., Skudlarski, P., Cohen, D. J., Gore, J. C., et al. (2005). fMRI activation of the fusiform gyrus and amygdala to cartoon characters but not to faces in a boy with autism. Neuropsychologia, 43(3), 373–385. doi:10.1016/j.neuropsychologia.2004.06.015.CrossRefPubMedGoogle Scholar
  12. Howell, D. C., Rogier, M., Yzerbyt, V., & Bestgen, Y. (1998). Statistical methods in human sciences. New York: Wadsworth.Google Scholar
  13. Hutton, S. B. (2008). Cognitive control of saccadic eye movements. Brain and Cognition, 68(3), 327–340. doi:10.1016/j.bandc.2008.08.021.CrossRefPubMedGoogle Scholar
  14. Jacob, S., Landeros-Weisenberger, A., & Leckman, J. F. (2009). Autism spectrum and obsessive-compulsive disorders: OC behaviors, phenotypes and genetics. Autism Research, 2(6), 293–311.CrossRefPubMedPubMedCentralGoogle Scholar
  15. Jemel, B., Mottron, L., & Dawson, M. (2006). Impaired face processing in autism: Fact or artifact? Journal of Autism and Developmental Disorders, 36(1), 91–106. doi:10.1007/s10803-005-0050-5.CrossRefPubMedGoogle Scholar
  16. Jones, W., & Klin, A. (2013). Attention to eyes is present but in decline in 2–6-month-old infants later diagnosed with autism. Nature, 504(7480), 427–431. doi:10.1038/nature12715.CrossRefPubMedPubMedCentralGoogle Scholar
  17. Katarzyna, C., Fred, V., & Ami, K. (2010). Limited attentional bias for faces in toddlers with autism spectrum disorders. Archives of General Psychiatry, 67(2), 178. doi:10.1001/archgenpsychiatry.2009.194.CrossRefGoogle Scholar
  18. Kaufman, J., Birmaher, B., Brent, D., Rao, U. M. A., Flynn, C., Moreci, P., et al. (1997). Schedule for affective disorders and schizophrenia for school-age children-present and lifetime version (K-SADS-PL): Initial reliability and validity data. Journal of the American Academy of Child & Adolescent Psychiatry, 36(7), 980–988.CrossRefGoogle Scholar
  19. Kaufman, A., & Kaufman, N. (2004). Kaufman Brief Intellifence Test (2nd ed.). Bloomington, MN: Pearson.Google Scholar
  20. Klin, A., Jones, W., Schultz, R., Volkmar, F., & Cohen, D. (2002). Visual fixation patterns during viewing of naturalistic social situations as predictors of social competence in individuals with autism. Archives of General Psychiatry, 59(9), 809. doi:10.1001/archpsyc.59.9.809.CrossRefPubMedGoogle Scholar
  21. Lopez, B. R., Lincoln, A. J., Ozonoff, S., & Lai, Z. (2005). Examining the relationship between executive functions and restricted, repetitive symptoms of autistic disorder. Journal of Autism and Developmental Disorders, 35(4), 445–460. doi:10.1007/s10803-005-5035-x.CrossRefPubMedGoogle Scholar
  22. Lord, C., Rutter, M., DiLavore, P., Risi, S., Gotham, K., & Bishop, S. (2012). Autism Diagnostic Observation Schedule (ADOS-2) (2nd ed.). Torrance, CA: Western Psychological Services.Google Scholar
  23. Luna, B., Doll, S. K., Hegedus, S. J., Minshew, N. J., & Sweeney, J. A. (2007). Maturation of executive function in autism. Biological Psychiatry, 61(4), 474–481. doi:10.1016/j.biopsych.2006.02.030.CrossRefPubMedGoogle Scholar
  24. Luna, B., Garver, K. E., Urban, T. A., Lazar, N. A., & Sweeney, J. A. (2004). Maturation of cognitive processes from late childhood to adulthood. Child Development, 75(5), 1357–1372. doi:10.1111/j.1467-8624.2004.00745.x.CrossRefPubMedGoogle Scholar
  25. Manoach, D. S., Lindgren, K. A., & Barton, J. J. S. (2004). Deficient saccadic inhibition in Asperger’s disorder and the social-emotional processing disorder. Journal of Neurology, Neurosurgery and Psychiatry, 75(12), 1719–1726. doi:10.1136/jnnp.2003.025981.CrossRefPubMedPubMedCentralGoogle Scholar
  26. McMahon, C. M., & Henderson, H. A. (2014). Error-monitoring in response to social stimuli in individuals with higher-functioning autism spectrum disorder. Developmental Science. doi:10.1111/desc.12220.PubMedPubMedCentralGoogle Scholar
  27. Mosconi, M. W., Kay, M., D’Cruz, A.-M., Seidenfeld, A., Guter, S., Stanford, L. D., & Sweeney, J. A. (2009). Impaired inhibitory control is associated with higher-order repetitive behaviors in autism spectrum disorders. Psychological Medicine, 39(9), 1559–1566. doi:10.1017/S0033291708004984.CrossRefPubMedPubMedCentralGoogle Scholar
  28. Mostert-Kerckhoffs, M. A. L., Staal, W. G., Houben, R. H., & de Jonge, M. V. (2015). Stop and change: Inhibition and flexibility skills are related to repetitive behavior in children and young adults with autism spectrum disorders. Journal of Autism and Developmental Disorders, 45(10), 3148–3158. doi:10.1007/s10803-015-2473-y.CrossRefPubMedPubMedCentralGoogle Scholar
  29. Sabatino, A., Rittenberg, A., Sasson, N. J., Turner-Brown, L., Bodfish, J. W., & Dichter, G. S. (2013). Functional neuroimaging of social and nonsocial cognitive control in autism. Journal of Autism and Developmental Disorders, 43(12), 2903–2913. doi:10.1007/s10803-013-1837-4.CrossRefPubMedPubMedCentralGoogle Scholar
  30. Sasson, N. J., Dichter, G. S., & Bodfish, J. W. (2012). Affective responses by adults with autism are reduced to social images but elevated to images related to circumscribed interests. PLoS ONE, 7(8), e42457. doi:10.1371/journal.pone.0042457.CrossRefPubMedPubMedCentralGoogle Scholar
  31. Sasson, N. J., Elison, J. T., Turner-Brown, L. M., Dichter, G. S., & Bodfish, J. W. (2011). Brief report: Circumscribed attention in young children with autism. Journal of Autism and Developmental Disorders, 41(2), 242–247. doi:10.1007/s10803-010-1038-3.CrossRefPubMedPubMedCentralGoogle Scholar
  32. Sasson, N. J., & Touchstone, E. W. (2014). Visual attention to competing social and object images by preschool children with autism spectrum disorder. Journal of Autism and Developmental Disorders, 44(3), 584–592. doi:10.1007/s10803-013-1910-z.CrossRefPubMedGoogle Scholar
  33. Sasson, N. J., Turner-Brown, L. M., Holtzclaw, T. N., Lam, K. S. L., & Bodfish, J. W. (2008). Children with autism demonstrate circumscribed attention during passive viewing of complex social and nonsocial picture arrays. Autism Research. doi:10.1002/aur.4.PubMedPubMedCentralGoogle Scholar
  34. Scahill, L., Riddle, M. A., McSwiggin-Hardin, M., Ort, S. I., King, R. A., Goodman, W. K., et al. (1997). Children’s Yale-Brown obsessive compulsive scale: reliability and validity. Journal of the American Academy of Child and Adolescent Psychiatry, 36(6), 844–852. doi:10.1097/00004583-199706000-00023.CrossRefPubMedGoogle Scholar
  35. Shin, N. Y., Lee, T. Y., Kim, E., & Kwon, J. S. (2014). Cognitive functioning in obsessive-compulsive disorder: A meta-analysis. Psychological medicine, 44(6), 1121–1130.CrossRefPubMedGoogle Scholar
  36. South, M., Ozonoff, S., & McMahon, W. M. (2005). Repetitive behavior profiles in Asperger syndrome and high-functioning autism. Journal of Autism and Developmental Disorders, 35(2), 145–158. doi:10.1007/s10803-004-1992-8.CrossRefPubMedGoogle Scholar
  37. Tottenham, N., Tanaka, J. W., Leon, A. C., McCarry, T., Nurse, M., Hare, T. A., et al. (2009). The NimStim set of facial expressions: Judgments from untrained research participants. Psychiatry Research, 168(3), 242–249. doi:10.1016/j.psychres.2008.05.006.CrossRefPubMedPubMedCentralGoogle Scholar
  38. Turner, M. A. (1999). Generating novel ideas: Fluency performance in high-functioning and learning disabled individuals with autism. Journal of Child Psychology and Psychiatry, 40(2), 189–201. doi:10.1111/1469-7610.00432.CrossRefPubMedGoogle Scholar
  39. Turner-Brown, L. M., Lam, K. S. L., Holtzclaw, T. N., Dichter, G. S., & Bodfish, J. W. (2011). Phenomenology and measurement of circumscribed interests in autism spectrum disorders. Autism, 15(4), 437–456. doi:10.1177/1362361310386507.CrossRefPubMedPubMedCentralGoogle Scholar
  40. Turner-Brown, L. M., Perry, T. D., Dichter, G. S., Bodfish, J. W., & Penn, D. L. (2008). Brief report: Feasibility of social cognition and interaction training for adults with high functioning autism. Journal of Autism and Developmental Disorders, 38(9), 1777–1784. doi:10.1007/s10803-008-0545-y.CrossRefPubMedPubMedCentralGoogle Scholar
  41. Watson, K. K., Miller, S., Hannah, E., Kovac, M., Damiano, C. R., Sabatino-DiCrisco, A., et al. (2015). Increased reward value of non-social stimuli in children and adolescents with autism. Frontiers in Psychology. doi:10.3389/fpsyg.2015.01026.PubMedPubMedCentralGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  • Antoinette Sabatino DiCriscio
    • 1
    • 7
  • Stephanie J. Miller
    • 2
  • Eleanor K. Hanna
    • 3
  • Megan Kovac
    • 4
  • Lauren Turner-Brown
    • 2
  • Noah J. Sasson
    • 5
  • Jeffrey Sapyta
    • 6
  • Vanessa Troiani
    • 7
  • Gabriel S. Dichter
    • 1
    • 2
    • 8
  1. 1.Department of Psychology and NeuroscienceThe University of North Carolina at Chapel HillChapel HillUSA
  2. 2.Carolina Institute for Developmental DisabilitiesThe University of North Carolina at Chapel Hill School of MedicineChapel HillUSA
  3. 3.Department of Psychology and NeuroscienceDuke UniversityDurhamUSA
  4. 4.School Psychology Program, School of EducationThe University of North Carolina at Chapel HillChapel HillUSA
  5. 5.School of Behavioral and Brain SciencesThe University of Texas at DallasRichardsonUSA
  6. 6.Department of Psychiatry and Behavioral SciencesDuke University School of MedicineDurhamUSA
  7. 7.Geisinger Health SystemGeisinger Autism and Developmental Medicine Institute (ADMI)LewisburgUSA
  8. 8.Department of PsychiatryThe University of North Carolina at Chapel HillChapel HillUSA

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