Journal of Autism and Developmental Disorders

, Volume 46, Issue 2, pp 603–614 | Cite as

Obstetrical Mode of Delivery and Childhood Behavior and Psychological Development in a British Cohort

  • Eileen A. Curran
  • John F. Cryan
  • Louise C. Kenny
  • Timothy G. Dinan
  • Patricia M. Kearney
  • Ali S. Khashan
Original Paper


The association between mode of delivery [specifically birth by Cesarean section (CS)] and induction of labor (IOL) psychological development at age 7 was assessed [including autism spectrum disorders (ASD), attention-deficit/hyperactivity disorder (ADHD) and behavioral difficulties]. The Millennium cohort study, a nationally representative UK cohort of children (including 13,141 children), was used. There was no association between planned CS and ASD [aOR 0.58; (95 % CI 0.19–1.79)] or ADHD [aOR 0.54; (95 % CI 0.18–1.64)] analyses. Induced vaginal delivery was significantly associated with behavioral difficulties in unadjusted [OR 1.26; (95 % CI 1.03–1.54)], but not adjusted analysis [OR 1.15; (95 % CI 0.82–1.60)]. There was no association between mode of delivery and ASD or ADHD in this cohort. Further research is needed to understand the relationship between mode of delivery and IOL and psychological development.


Autism spectrum disorder ADHD Mode of delivery Induction of labor 

Supplementary material

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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Eileen A. Curran
    • 1
  • John F. Cryan
    • 2
  • Louise C. Kenny
    • 1
  • Timothy G. Dinan
    • 3
  • Patricia M. Kearney
    • 4
  • Ali S. Khashan
    • 1
    • 4
  1. 1.The Irish Centre for Fetal and Neonatal Translational Research (INFANT), Department of Obstetrics and GynaecologyUniversity College CorkCorkIreland
  2. 2.APC Microbiome Institute, Department of Anatomy and NeuroscienceUniversity College CorkCorkIreland
  3. 3.APC Microbiome Institute, Department of PsychiatryUniversity College CorkCorkIreland
  4. 4.Department of Epidemiology and Public HealthUniversity College CorkCorkIreland

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