Journal of Autism and Developmental Disorders

, Volume 45, Issue 10, pp 3255–3261 | Cite as

Low but Increasing Prevalence of Autism Spectrum Disorders in a French Area from Register-Based Data

  • Marit Maria Elisabeth van BakelEmail author
  • Malika Delobel-Ayoub
  • Christine Cans
  • Brigitte Assouline
  • Pierre-Simon Jouk
  • Jean-Philippe Raynaud
  • Catherine Arnaud
Original Paper


Register-based prevalence rates of childhood autism (CA), Asperger’s syndrome (AS) and other autism spectrum disorders (ASD) were calculated among children aged 7 years old of the 1997–2003 birth cohorts, living in four counties in France. The proportion of children presenting comorbidities was reported. 1123 children with ASD were recorded (M/F ratio: 4.1), representing an overall prevalence rate of 36.5/10,000 children (95 % CI 34.4–38.7): 8.8/10,000 for CA (95 % CI 7.8–9.9), 1.7/10,000 for AS (95 % CI 1.3–2.3) and 25.9/10,000 for other ASD (95 % CI 24.2–27.8). ASD prevalence significantly increased (p < 0.0001) during the period under study. The proportion of children with an intellectual disability was 47.3 %, all other comorbidities were present in less than 5 % of the cases.


Autism spectrum disorder Population register Prevalence Comorbidities 


Conflict of interest

All authors declare that they have no conflict of interest in relation to this study.

Ethical Standards

The study was carried out according to the French regulations of individual privacy. Parents who agreed to participate signed an informed consent form prior to inclusion of their child the study. The National Commission on Informatics and Liberties (CNIL) authorized the treatment and digitalization of the nominative data.


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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Marit Maria Elisabeth van Bakel
    • 1
    Email author
  • Malika Delobel-Ayoub
    • 2
    • 3
  • Christine Cans
    • 4
  • Brigitte Assouline
    • 5
  • Pierre-Simon Jouk
    • 6
    • 7
  • Jean-Philippe Raynaud
    • 2
    • 3
    • 8
  • Catherine Arnaud
    • 2
    • 3
    • 9
  1. 1.Register for Severely Disabled Children and Perinatal Observatory (RHEOP)GrenobleFrance
  2. 2.INSERM U.1027ToulouseFrance
  3. 3.Paul-Sabatier UniversityToulouseFrance
  4. 4.Themas Team, UMR 5525Joseph Fourier UniversityGrenobleFrance
  5. 5.Autism Resource Centre of the Rhone-Alpes RegionSt-EgreveFrance
  6. 6.Department of Genetics and ProcreationUniversity Hospital GrenobleGrenobleFrance
  7. 7.DYCTIM Team, UMR 5525 TIMC-IMAGJoseph Fourier University HospitalGrenobleFrance
  8. 8.Department of Child PsychiatryLa Grave University HospitalToulouseFrance
  9. 9.Department of Clinical EpidemiologyPurpan University HospitalToulouseFrance

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