Atypical Neurophysiology Underlying Episodic and Semantic Memory in Adults with Autism Spectrum Disorder
- 739 Downloads
Individuals with autism spectrum disorder (ASD) show atypicalities in episodic memory (Boucher et al. in Psychological Bulletin, 138 (3), 458–496, 2012). We asked participants to recall the colours of a set of studied line drawings (episodic judgement), or to recognize line drawings alone (semantic judgement). Cycowicz et al. (Journal of Experimental Child Psychology, 65, 171–237, 2001) found early (300 ms onset) posterior old–new event-related potential effects for semantic judgements in typically developing (TD) individuals, and occipitally focused negativity (800 ms onset) for episodic judgements. Our results replicated findings in TD individuals and demonstrate attenuated early old–new effects in ASD. Late posterior negativity was present in the ASD group, but was not specific to this time window. This non-specificity may contribute to the atypical episodic memory judgements characteristic of individuals with ASD.
KeywordsMemory Episodic Semantic Source memory Autism spectrum disorder Event-related potential
Full intelligence quotient
Performance intelligence quotient
The authors would like to thank the individuals who participated in the study. The first author was supported by a research studentship from the Department of Psychology, City University London.
Conflict of interest
The authors declare that they have no conflict of interest.
- American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders DSM-IV-TR (4th ed Revised ed.). Washington, DC: APA.Google Scholar
- Baron-Cohen, S., Wheelwright, S., Skinner, R., Martin, J., & Clubley, E. (2001). The autism-spectrum quotient (AQ): Evidence from asperger syndrome/high-functioning autism, males and females, scientists and mathematicians. Journal of Autism and Developmental Disorders, 31, 5–17. doi: 10.1023/A:1005653411471.PubMedCrossRefGoogle Scholar
- Buckner, R., & Tulving, E. (1995). Neuroimaging studies of memory: Theory and recent PET results. In F. Boller & J. Grafman (Eds.), Handbook of neuropsychology (Vol. 10). Amsterdam: Elsevier.Google Scholar
- Courchesne, E., Kilman, B. A., Galambos, R., & Lincoln, A. J. (1984). Autism: Processing of novel auditory information assessed by event-related brain potentials. Electroencephalography and Clinical Neurophysiology, 59(3), 238–248. doi: 10.1016/0168-5597(84)90063-7.
- Düzel, E., Yonelinas, A. P., Mangun, G. R., Heinze, H. J., & Tulving, E. (1997). Event-related brain potential correlates of two states of conscious awareness in memory. Proceedings of the National Academy of Sciences of the United States of America, 94(11), 5973–5978. doi: 10.1073/pnas.94.11.5973.PubMedCentralPubMedCrossRefGoogle Scholar
- Friedman, D., & Johnson, J. R. (2000). Event-related potential (ERP) studies of memory encoding and retrieval: A selective review. Microscopy Research and Technique, 51, 6–28. doi: 10.1002/1097-0029(20001001)51:1<6:AID-JEMT2>3.0.CO;2-R.PubMedCrossRefGoogle Scholar
- Johnson, R. J. (1995). Event-related potential insights into the neurobiology of memory systems. In F. Boller & J. Grafman (Eds.), Handbook of neuropsychology (Vol. 10, pp. 135–163). Amsterdam: Elsevier.Google Scholar
- Kuhl, P. K., Coffey-Corina, S., Padden, D., & Dawson, G. (2005). Links between social and linguistic processing of speech in preschool children with autism: Behavioral and electrophysiological measures. Developmental Science, 8, F1–F12. doi: 10.1111/j.1467-7687.2004.00384.x.PubMedCrossRefGoogle Scholar
- Lepisto, T., Silokallio, S., Nieminen-von Wendt, T., Alku, P., Naatanen, R., & Kujala, T. (2006). Auditory perception and attention as reflected by the brain event-related potentials in children with asperger syndrome. Clinical Neurophysiology, 117(10), 2161–2171. doi: 10.1016/j.clinph.2006.06.709.PubMedCrossRefGoogle Scholar
- Lind, S., & Bowler, D. M. (2008). Episodic memory and autonoetic consciousness in autistic spectrum disorders: The roles of self-awareness, representational abilities, and temporal cognition. In J. M. Boucher & D. M. Bowler (Eds.), Memory in autism: Theory and evidence (pp. 166–187). Cambridge: Cambridge University Press. doi: 10.1017/CBO9780511490101.011.CrossRefGoogle Scholar
- Lord, C., Risi, S., Lambrecht, L., Cook, E. H., Leventhal, B. L., DiLavore, P. C., et al. (2000). The autism diagnostic observation schedule—generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30(3), 205–223. doi: 10.1023/A:1005592401947.PubMedCrossRefGoogle Scholar
- Luck, S. J. (2010). “Is it legitimate to compare conditions with different numbers of trials?” Retrieved from http://erpinfo.org/Members/sjluck/Mean_Peak_Noise.pdf/view (on September 28, 2010).
- Massand, E., Bowler, D. M., Mottron, L., Hosein, A., & Jemel, B. (2013). ERP correlates of recognition memory in autism spectrum disorder. Journal of Autism and Developmental Disorders. Online First. http://link.springer.com/journal/10803.
- Naatanen, R. (1992). Attention and brain function. Hillsdale, New Jersey: Erlbaum.Google Scholar
- Nelson, D. L. (1979). Remembering pictures and words: Appearance, significance, and name. In L. S. Cermak & F. I. M. Craik (Eds.), Levels of processing in human memory (pp. 45–76). Hillsdale, NJ: Erlbaum.Google Scholar
- Paivio, A. (1986). Mental representations: A dual coding approach. New York: Oxford University Press.Google Scholar
- Schacter, D. L., & Tulving, E. (1994). What are the memory systems of 1994? In D. L. Schacter & E. Tulving (Eds.), Memory systems 1994 (pp. 1–38). Cambridge: MIT Press.Google Scholar
- Spreng, R. N., Mar, R. A., & Kim, A. S. N. (2009). The common neural basis of autobiographical memory, prospection, navigation, theory of mind and the default mode: A quantitative meta-analysis. Journal of Cognitive Neuroscience, 21, 489–510. doi: 10.1162/jocn.2008.21029.PubMedCrossRefGoogle Scholar
- Squire, L. R., & Kandel, E. R. (1999). Memory: From mind to molecules (Vol. 69). New York: W.H. Freeman.Google Scholar
- Squire, L. R., & Knowlton, B. (2000). The medial temporal love, the hippocampus, and the memory systems of the brain. In M. S. Gazzaniga (Ed.), The new cognitive neurosciences. Cambridge, MA: MIT Press.Google Scholar
- Trott, C. T., Friedman, D., Ritter, W., Fabiani, M., & Snodgrass, J. G. (1999). Episodic priming and memory for temporal source: Event-related potentials reveal age-related differences in prefronal functioning. Psychology and Aging, 14(3), 390–413. doi: 10.1037/0882-7922.214.171.1240.PubMedCrossRefGoogle Scholar