Atypical Gaze Following in Autism: A Comparison of Three Potential Mechanisms
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In order to evaluate the following potential mechanisms underlying atypical gaze following in autism, impaired reflexive gaze following, difficulty integrating gaze and affect, or reduced understanding of the referential significance of gaze, we administered three paradigms to young children with autism (N = 21) and chronological (N = 21) and nonverbal mental age (N = 21) matched controls. Children with autism exhibited impaired reflexive gaze following. The absence of evidence of integration of gaze and affect, regardless of diagnosis, indicates ineffective measurement of this construct. Reduced gaze following was apparent among children with autism during eye-tracking and in-person assessments. Word learning from gaze cues was better explained by developmental level than autism. Thus, gaze following may traverse an atypical, rather than just delayed, trajectory in autism.
KeywordsResponse to joint attention Autism Reflexive gaze following Word learning
We are very grateful to all of the children and families who participated in our study. We would like to thank Devi Beck-Pancer and Brian Nguyen for their invaluable contributions to stimuli design. We would like to thank the following people for help with data collection and/or coding: Mithi del Rosario, Kia Dela Cruz, Lovella Gomez, Nancy Lê, Jane Lee, Jennifer Nicole Loa, Brigid McCarthy, Christine Park. Connie Kasari provided excellent guidance on study design. This work was supported by National Institutes of Health Grant R01-HD40432 to Scott P. Johnson, NICHD/NIH Autism Centers of Excellence (ACE) Grant Number P50-HD-055784 to Susan Bookheimer, and the FPR-UCLA Center for Culture, Brain and Development. We would also like to thank reviewers for their extremely helpful comments.
- Bishop, S. L., Guthrie, W., Coffing, M., & Lord, C. (2011). Convergent validity of the Mullen Scales of Early Learning and the differential ability scales in children with autism spectrum disorders. American Journal of Intellectual and Developmental Disabilities, 16(5), 331–343.CrossRefGoogle Scholar
- Constantino, J. N., & Gruber, C. P. (2002). The social responsiveness scale. Los Angeles: Western Psychological Services.Google Scholar
- Dawson, G., Bernier, R., & Ring, R. H. (2012). Social attention: A possible early indicator of efficacy in autism clinical trials. Journal of Neurodevelopmental Disorders, 4(1). doi: 10.1186/1866-1955-4-11.
- Elliot, C. D. (1990). Differential ability scales. San Antonio, TX: The psychological corporation.Google Scholar
- Gliga, T., Elsabbagh, M., Hudry, K., Charman, T., & Johnson, M. H. (2012). Gaze following, gaze reading, and word learning in children at risk for autism. Child Development, 83(3), 926–938.Google Scholar
- Goldberg, M. C., Mostow, A. J., Vecera, S. P., Gidley Larson, J. C., Mostofsky, S. H., Mahone, E. H., et al. (2008). Evidence for impairments in using static line drawings of eye gaze cues to orient visual-spatial attention in children with high functioning autism. Journal of Autism and Developmental Disorders, 38, 1405–1413.PubMedCrossRefGoogle Scholar
- Heitanen, J. K., & Leppänen, J. M. (2003). Does facial expression affect attention orientation by gaze direction cues? Journal of Experimental Psychology, 29(6), 1228–1243.Google Scholar
- Mullen, E. M. (1995). Mullen Scales of Early Learning (AGS ed.). Circle Pines, MN: American Guidance Service.Google Scholar
- Rombough, A., & Iarocci, G. (in press). Orienting in response to gaze and the social use of gaze among children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 1–13.Google Scholar
- Rozga, A., Hutman, T., Young, G. S., Rogers, S. J., Ozonoff, S., Dapretto, M., et al. (2011). Behavioral profiles of affected and unaffected siblings of children with autism: Contribution of measures of mother–infant interaction and nonverbal communication. Journal of Autism and Developmental Disorders, 41, 287–301.PubMedCrossRefGoogle Scholar
- Scaife, M., & Bruner, J. S. (1975). The capacity for joint visual attention in the infant. Nature, 265–266.Google Scholar
- Schilbach, L., Timmermans, B., Reddy, V., Costall, A., Bente, G., Schlicht, T., & Vogeley, K. (in press). Toward a second-person neuroscience. Behavioral and Brain Sciences. Google Scholar
- Schopler, E., Van Bourgondien, M., Wellman, J., & Love, S. (2010). Childhood Autism Rating Scale—Second edition (CARS2): Manual. Los Angeles: Western Psychological Services.Google Scholar
- Tipples, J. (2006). Fear and fearfulness potentiate automatic orienting to eye gaze. Cognition and Emotion, 26(2), 309–320.Google Scholar
- Yu, C., & Smith, L. B. (2012). Embodied attention and word learning by toddlers. Cognition.Google Scholar