Journal of Autism and Developmental Disorders

, Volume 43, Issue 5, pp 1184–1195

Sensitivity and Specificity of Proposed DSM-5 Criteria for Autism Spectrum Disorder in Toddlers

  • Marianne L. Barton
  • Diana L. Robins
  • Dasal Jashar
  • Laura Brennan
  • Deborah Fein
Original Paper

Abstract

Autism spectrum disorder (ASD) diagnosis is based on behavioral presentation; changes in conceptual models or defining behaviors may significantly impact diagnosis and uptake of ASD-specific interventions. The literature examining impact of DSM-5 criteria is equivocal. Toddlers may be especially vulnerable to the stringent requirements of impairment in all three social-communication symptoms and two restricted/repetitive symptoms. Receiver operating characteristic (ROC) curves identified optimal cutoffs for sums of ADOS and ADI-R criteria mapped to each criterion for 422 toddlers. The optimal modification of DSM-5 criteria (sensitivity = 0.93, specificity = 0.74) required meeting the ROC-determined cutoffs for 2/3 Domain A criteria and 1 point for 1/4 Domain B criteria. This modification will help insure that ASD is identified accurately in young children, facilitating ASD-specific early intervention.

Keywords

Autism spectrum disorder DSM-5 Toddlers Diagnosis 

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Copyright information

© Springer Science+Business Media New York 2013

Authors and Affiliations

  • Marianne L. Barton
    • 1
  • Diana L. Robins
    • 2
  • Dasal Jashar
    • 1
  • Laura Brennan
    • 1
  • Deborah Fein
    • 1
  1. 1.Department of PsychologyUniversity of ConnecticutStorrsUSA
  2. 2.Department of PsychologyGeorgia State UniversityAtlantaUSA

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