Journal of Autism and Developmental Disorders

, Volume 43, Issue 6, pp 1356–1366

Executive Function in MCDD and PDD-NOS: A Study of Inhibitory Control, Attention Regulation and Behavioral Adaptivity

  • Sophie van Rijn
  • Leo de Sonneville
  • Bertine Lahuis
  • Jolijn Pieterse
  • Herman van Engeland
  • Hanna Swaab
Original Paper

Abstract

A proportion of children within the autism spectrum is at risk for severe deregulation of thought, emotion and behaviour resulting in (symptoms of) psychotic disorders over the course of development. In an attempt to identify this subgroup, children with PDD-NOS, subtype MCDD (n = 24) were compared to children with PDD-NOS (n = 23) on executive function (EF) skills. Significant differences emerged, always to the disadvantage of the children with PDD-NOS, subtype MCDD on various EF measures. The findings suggest compromised attention regulation and impaired inhibitory control in children with MCDD, which may help explain high levels of thought problems which are frequently observed in these children. Our findings provide evidence for recognizing a PDD subcategory of MCDD that is of specific interest with regard to long-term developmental risks involved.

Keywords

MCDD PDD Sustained attention Executive function Risk factors Psychosis ANT 

Copyright information

© Springer Science+Business Media New York 2012

Authors and Affiliations

  • Sophie van Rijn
    • 1
    • 2
  • Leo de Sonneville
    • 1
    • 2
  • Bertine Lahuis
    • 3
    • 4
  • Jolijn Pieterse
    • 1
  • Herman van Engeland
    • 4
  • Hanna Swaab
    • 1
    • 2
  1. 1.Department of Clinical Child and Adolescent Studies, Faculty of Social and Behavioral SciencesLeiden UniversityLeidenThe Netherlands
  2. 2.Leiden Institute of Brain and CognitionLeidenThe Netherlands
  3. 3.Karakter Child and Adolescent PsychiatryUniversity Medical Center St. RadboudNijmegenThe Netherlands
  4. 4.Department of Child- and Adolescent PsychiatryUniversity Medical Center Utrecht and the Rudolph Magnus Institute of NeurosciencesUtrechtThe Netherlands

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