Journal of Autism and Developmental Disorders

, Volume 42, Issue 8, pp 1671–1683 | Cite as

Acupuncture for Children with Autism Spectrum Disorders: A Systematic Review of Randomized Clinical Trials

  • Myeong Soo LeeEmail author
  • Tae-Young Choi
  • Byung-Cheul Shin
  • Edzard Ernst
Original Paper


This study aimed to assess the effectiveness of acupuncture as a treatment for autism spectrum disorders (ASD). We searched the literature using 15 databases. Eleven randomized clinical trials (RCTs) met our inclusion criteria. Most had significant methodological weaknesses. The studies’ statistical and clinical heterogeneity prevented us from conducting a meta-analysis. Two RCTs found that acupuncture plus conventional language therapy was superior to sham acupuncture plus conventional therapy. Two other RCTs found that acupuncture produced significant effects compared with conventional language therapy or complex interventions. Three RCTs suggested that acupuncture plus conventional therapies had beneficial effects compared with conventional therapy alone. Four more RCTs reported that subjects who received acupuncture experienced significant effects compared with subjects who were waitlisted or received no treatment. The results of these studies provide mixed evidence of acupuncture’s effectiveness as a treatment for ASD symptoms.


Acupuncture Complementary medicine Autism spectrum disorders Effectiveness Systematic review 



Myeong Soo Lee and Tae-Young Choi were supported by KIOM (K11111).

Conflict of interest

None declare.

Supplementary material

10803_2011_1409_MOESM1_ESM.doc (131 kb)
Supplementary material 1 (DOC 131 kb)


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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Myeong Soo Lee
    • 1
    Email author
  • Tae-Young Choi
    • 1
  • Byung-Cheul Shin
    • 2
  • Edzard Ernst
    • 3
  1. 1.Brain Disease Research CenterKorea Institute of Oriental MedicineDaejeonSouth Korea
  2. 2.School of Korean MedicinePusan National UniversityYangsanSouth Korea
  3. 3.Complementary Medicine, Peninsula Medical School, University of ExeterExeterUK

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