Brief Report: Association Between Behavioral Features and Gastrointestinal Problems Among Children with Autism Spectrum Disorder
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Recent reports suggest certain behaviors among children with autism spectrum disorders (ASD) may indicate underlying gastro-intestinal (GI) problems, and that the presence of these behaviors may help alert primary care providers to the need to evaluate a child with ASD for GI problems. The purpose of this population-based study of 487 children with ASD, including 35 (7.2%) with a medically documented history of GI problems, was to compare behavioral features of children with and without a history of GI problems. Unusual sleeping or eating habits and oppositional behavior were significantly associated with GI problems. These behaviors, however, were frequent in both children with and without GI problems, suggesting they may have limited utility in a screening capacity for GI problems.
KeywordsAutism spectrum disorder Gastrointestinal
This work was supported by a grant from the Autism Science Foundation and by the Centers for Disease Control and Prevention through Cooperative Agreements UR3/CCU523235 and UR3/DD000078 as part of the Autism and Developmental Disabilities Monitoring (ADDM) Network. We gratefully acknowledge ADDM project coordinators, clinician reviewers, abstractors, ADDM investigators who contributed to the surveillance project and data collection. We also thank Dr. Lisa Miller for her helpful comments on an earlier version of this manuscript.
- Centers for Disease Control Prevention (CDC). (2009). Prevalence of autism spectrum disorders—Autism and developmental disabilities monitoring network, United States, 2006. Morbidity and Mortality Weekly Report, Surveillance Summaries, 58, 1–20.Google Scholar
- Richler, J., Luyster, R., Risi, S., Hsu, W. L., Dawson, G., Bernier, R., et al. (2006). Is there a ‘regressive phenotype’ of autism spectrum disorder associated with the measles-mumps-rubella vaccine? A CPEA Study. Journal of Autism and Developmental Disorders, 36(3), 299–316.PubMedCrossRefGoogle Scholar
- Wang, L. W., Tancredi, D. J., & Thomas, D. W. (2011). The prevalence of gastrointestinal problems in children across the United States with autism spectrum disorders from families with multiple affected members. Journal of Developmental and Behavioral Pediatrics, 32(5), 351–360.PubMedCrossRefGoogle Scholar
- Williams, K. C., Fuchs, G. J., Furuta, G. T., Marcon, M. A., & Coury, D. L. (2010). Clinical features associated with GI symptoms in autism spectrum disorders (ASD). Gastroenterology, 138(5, Suppl 1), S-74.Google Scholar