Journal of Autism and Developmental Disorders

, Volume 42, Issue 4, pp 643–646 | Cite as

Further Commentary on Mitochondrial Dysfunction in Autism Spectrum Disorder: Assessment and Treatment Considerations

  • Stephen R. Dager
  • Neva M. Corrigan
  • Annette Estes
  • Dennis W. W. Shaw
Letter to the Editor

Abstract

The authors respond to a recent letter (Rossignol and Frye 2011) critical of their paper, “Proton magnetic resonance spectroscopy and MRI reveal no evidence for brain mitochondrial dysfunction in children with autism spectrum disorder” (Corrigan et al. 2011). Further considerations regarding the assessment of mitochondrial dysfunction in autism spectrum disorder, and related treatment considerations, are discussed.

Keywords

Autism Developmental disorders MRS MRI Mitochondrial disorders Brain lactate 

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Copyright information

© Springer Science+Business Media, LLC 2011

Authors and Affiliations

  • Stephen R. Dager
    • 1
    • 2
    • 3
  • Neva M. Corrigan
    • 1
  • Annette Estes
    • 2
    • 4
  • Dennis W. W. Shaw
    • 1
    • 5
  1. 1.Department of RadiologyUniversity of WashingtonSeattleUSA
  2. 2.University of Washington Autism CenterSeattleUSA
  3. 3.Department of BioengineeringUniversity of WashingtonSeattleUSA
  4. 4.Department of Speech and Hearing SciencesUniversity of WashingtonSeattleUSA
  5. 5.Seattle Children’s HospitalSeattleUSA

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