Journal of Autism and Developmental Disorders

, Volume 41, Issue 3, pp 302–310 | Cite as

Comparing Autism, PDD-NOS, and Other Developmental Disabilities on Parent-Reported Behavior Problems: Little Evidence for ASD Subtype Validity

Original Paper

Abstract

Studies on the distinction between Autistic Disorder (AD) and Pervasive Developmental Disorder Not Otherwise Specified (PDD-NOS) have been inconclusive. This study examined the validity of PDD-NOS by comparing it to AD and other developmental disorders (DD) on parent-reported behavior problems. Fifty-four children with PDD-NOS were individually matched on age and non-verbal IQ to 54 children with AD and 54 children with DD. Groups were compared on select subscales of the Child Behavior Checklist. High rates of psychopathology were observed in both ASD groups. The only difference between PDD-NOS and AD groups was higher scores in the PDD-NOS group on two items measuring Anxiety/Depression. Cognitive functioning may be a more salient variable than subtype when studying psychopathology in individuals with ASDs.

Keywords

Autism PDD-NOS Subtypes Classification Validity Behavior problems 

References

  1. Abrahams, B. S., & Geschwind, D. H. (2008). Advances in autism genetics: On the threshold of a new neurobiology. Nature Reviews Genetics, 9, 341–355.CrossRefPubMedGoogle Scholar
  2. Achenbach, T., & Rescorla, L. A. (2001). Manual for the ASEBA school-age forms and profiles. Burlington, VT: University of Vermont Research Center for Children, Youth, and Families.Google Scholar
  3. American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders—text revised (4th ed.). Washington, DC: APA.Google Scholar
  4. Amiet, C., Gourfinkel-An, I., Bouzamondo, A., Tordjman, S., Baulac, M., Lechat, P., et al. (2008). Epilepsy in autism is associated with intellectual disability and gender: Evidence from a meta-analysis. Biological Psychiatry, 64, 577–582.CrossRefPubMedGoogle Scholar
  5. Beglinger, L. J., & Smith, T. H. (2001). A review of subtyping in autism and proposed dimensional classification model. Journal of Autism and Developmental Disorders, 31, 411–422.CrossRefPubMedGoogle Scholar
  6. Bishop, D. V., & Norbury, C. F. (2002). Exploring the borderlands of autistic disorder and specific language impairment: A study using standardized diagnostic instruments. Journal of Child Psychology and Psychiatry, 43, 917–929.CrossRefPubMedGoogle Scholar
  7. Buitelaar, J. K., Van der Gaag, R., Klin, A., & Volkmar, F. (1999). Exploring the boundaries of pervasive developmental disorder not otherwise specified: Analyses of data from the DSM-IV autistic disorder field trial. Journal of Autism and Developmental Disorders, 29, 33–43.CrossRefPubMedGoogle Scholar
  8. Cantwell, D. P. (1996). Classification of child and adolescent pyschopathology. Journal of Child Psychology and Psychiatry, 37, 3–12.CrossRefPubMedGoogle Scholar
  9. Einfeld, S. L., & Tonge, B. J. (1996). Population prevalence of psychopathology in children and adolescents with intellectual disability: Epidemiological findings. Journal of Intellectual Disability Research, 40, 99–109.CrossRefPubMedGoogle Scholar
  10. Fombonne, E. (2005). Epidemiological studies of pervasive developmental disorders. In F. R. Volkmar, R. Paul, A. Klin, & D. Cohen (Eds.), Handbook of autism and pervasive developmental disorders (pp. 42–69). Hoboken, NJ: Wiley.Google Scholar
  11. Frith, U. (2001). What framework should we use for understanding developmental disorders? Developmental Neuropsychology, 20, 555–563.CrossRefPubMedGoogle Scholar
  12. Gadow, K. D., DeVincent, C. J., Pomeroy, J., & Azizian, A. (2004). Psychiatric symptoms in preschool children with PDD in clinic and comparison samples. Journal of Autism and Developmental Disorders, 34, 379–393.CrossRefPubMedGoogle Scholar
  13. Gadow, K. D., DeVincent, C. J., Pomeroy, J., & Azizian, A. (2005). Comparison of DSM-IV symptoms in elementary school-age children with PDD versus clinic and community samples. Autism, 9, 392–415.CrossRefPubMedGoogle Scholar
  14. Kim, J. A., Szatmari, P., Bryson, S. E., Streiner, D. L., & Wilson, F. J. (2000). The prevalence of anxiety and mood problems among children with autism and Asperger syndrome. Autism, 4, 117–132.CrossRefGoogle Scholar
  15. Kraemer, H. C., Shrout, P. E., & Rubio-Stipec, M. (2007). Developing the diagnostic and statistical manual V: What will “statistical” mean? Social Psychiatry and Psychiatric Epidemiology, 42, 259–267.CrossRefPubMedGoogle Scholar
  16. Lecavalier, L. (2006). Behavioral and emotional problems in young people with pervasive developmental disorders: Relative prevalence, effects of subject characteristics, and empirical classification. Journal of Autism and Developmental Disorders, 36, 1101–1114.CrossRefPubMedGoogle Scholar
  17. Leyfer, O. T., Folstein, S. E., Bacalman, S., Davis, N. O., Dinh, E., Morgan, J., et al. (2006). Comorbid psychiatric disorders in children with autism: Interview development and rates of disorders. Journal of Autism and Developmental Disorders, 36, 849–861.CrossRefPubMedGoogle Scholar
  18. Lord, C., Leventhal, B. L., & Cook, E. (2001). Quantifying the phenotype in autism spectrum disorders. American Journal of Medical Genetics, 105, 36–38.CrossRefPubMedGoogle Scholar
  19. Lord, C., Rutter, M., DiLavore, P., & Risi, S. (1999). Autism diagnostic observation schedule-generic. Los Angeles, CA: Western Psychological Services.Google Scholar
  20. Mahoney, W. J., Szatmari, P., MacLean, J., Bryson, S. E., Bartolucci, G., Walter, S. D., et al. (1998). Reliability and accuracy of differentiating pervasive developmental disorder subtypes. Journal of the American Academy of Child and Adolescent Psychiatry, 37, 278–285.CrossRefPubMedGoogle Scholar
  21. Munson, J., Dawson, G., Sterling, L., Beauchaine, T., Zhou, A., Koehler, E., et al. (2008). Evidence for latent classes of IQ in young children with autism spectrum disorder. American Journal on Mental Retardation, 113, 439–452.CrossRefPubMedGoogle Scholar
  22. Pandolfi, V., Magyar, C. I., & Dill, C. A. (2009). Confirmatory factor analysis of the child behavior checklist 1.5–5 in a sample of children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 39, 986–995.CrossRefPubMedGoogle Scholar
  23. Pearson, D. A., Loveland, K. A., Lachar, D., Lane, D. M., Reddoch, S. L., Mansour, R., et al. (2006). A comparison of behavioral and emotional functioning in children and adolescents with autistic disorder and PDD-NOS. Child Neuropsychology, 12, 321–333.CrossRefPubMedGoogle Scholar
  24. Robins, E., & Guze, S. B. (1970). Establishment of diagnostic validity in psychiatric illness: Its application to schizophrenia. American Journal of Psychiatry, 126, 983–987.PubMedGoogle Scholar
  25. Shattuck, P. T., Seltzer, M. M., Greenberg, J. S., Orsmond, G. I., Bolt, D., Kring, S., et al. (2007). Change in autism symptoms and maladaptive behaviors in adolescents and adults with an autism spectrum disorder. Journal of Autism and Developmental Disorders, 37, 1735–1747.CrossRefPubMedGoogle Scholar
  26. Simonoff, E., Pickles, A., Charman, T., Chandler, S., Loucas, T., & Baird, G. (2008). Psychiatric disorders in children with autism spectrum disorders: Prevalence, comorbidity, and associated factors in a population derived sample. Journal of the American Academy of Child and Adolescent Psychiatry, 47, 921–929.CrossRefPubMedGoogle Scholar
  27. Skuse, D. H. (2007). Rethinking the nature of genetic vulnerability to autistic spectrum disorders. Trends in Genetics, 8, 387–395.CrossRefGoogle Scholar
  28. Sponheim, E., & Skjeldal, O. (1998). Autism and related disorders: Epidemiological findings in a Norwegian study using ICD-10 diagnostic criteria. Journal of Autism and Developmental Disorders, 28, 217–227.CrossRefPubMedGoogle Scholar
  29. Sukhodolsky, D. G., Scahill, L., Gadow, K. G., Arnold, L. E., Aman, M. G., McDougle, C. J., et al. (2007). Parent-rated anxiety symptoms in children with pervasive developmental disorders: Frequency and association with core autism symptoms and cognitive functioning. Journal of Abnormal Child Psychology, 36, 117–128.CrossRefPubMedGoogle Scholar
  30. Szatmari, P. (2000). The classification of autism, Asperger’s syndrome, and pervasive developmental disorder. Canadian Journal of Psychiatry, 45, 731–738.Google Scholar
  31. Towbin, K. (2005). Pervasive developmental disorder not otherwise specified. In F. R. Volkmar, R. Paul, A. Klin, & D. J. Cohen (Eds.), Handbook of autism and pervasive developmental disorders (3rd ed.). New York: Wiley.Google Scholar
  32. Verte, S., Geurts, H. M., Roeyers, H., Oosterlaan, J., & Sergeant, J. A. (2006). Executive functioning in children with an autism spectrum disorder: Can we differentiate within the spectrum? Journal of Autism and Developmental Disorders, 36, 351–372.CrossRefPubMedGoogle Scholar
  33. Volkmar, F. R., Klin, A., Siegel, B., Szatmari, P., Lord, C., Campbell, M., et al. (1994). Field trial for autistic disorder in DSM-IV. American Journal of Psychiatry, 151, 1361–1367.PubMedGoogle Scholar
  34. Wesibrot, D. M., Gadow, K. D., DeVincent, C. J., & Pomeroy, J. (2005). The presentation of anxiety in children with pervasive developmental disorders. Journal of Child and Adolescent Psychopharmacology, 15, 477–496.CrossRefGoogle Scholar
  35. Witwer, A. N., & Lecavalier, L. (2008). Validity of autism spectrum disorder subtypes. Journal of Autism and Developmental Disorders, 38, 1611–1624.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  1. 1.Ohio State UniversityColumbusUSA

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