Journal of Autism and Developmental Disorders

, Volume 40, Issue 11, pp 1389–1402

Onset Patterns Prior to 36 Months in Autism Spectrum Disorders

  • Luther G. Kalb
  • J. K. Law
  • Rebecca Landa
  • Paul A. Law
Original Paper

Abstract

The present study investigated differences among children with three different patterns of autism symptom onset: regression, plateau, and no loss and no plateau. Cross-sectional data were collected from parents of children aged 3–17 years with an autism spectrum disorder (n = 2,720) who were recruited through a US-based online research database. Parental report of developmental characteristics was assessed through a parent questionnaire, and current autism symptoms were measured via the Social Responsiveness Scale and Social Communication Questionnaire. Multivariate analyses indicated that children with regression had a distinct developmental pattern marked by less delayed early development. However, following regression, these children evinced elevated autism symptom scores and an increased risk for poorer outcomes when compared with the other onset groups.

Keywords

Autism Pervasive developmental disorders Regression Symptom Onset pattern 

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Copyright information

© Springer Science+Business Media, LLC 2010

Authors and Affiliations

  • Luther G. Kalb
    • 1
  • J. K. Law
    • 2
    • 3
  • Rebecca Landa
    • 1
    • 4
  • Paul A. Law
    • 2
    • 3
  1. 1.Center for Autism and Related DisordersKennedy Krieger InstituteBaltimoreUSA
  2. 2.Department of Medical InformaticsKennedy Krieger InstituteBaltimoreUSA
  3. 3.Department of PediatricsThe Johns Hopkins University School of MedicineBaltimoreUSA
  4. 4.Department of Psychiatry and Behavioral SciencesThe Johns Hopkins University School of MedicineBaltimoreUSA

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