Onset Patterns Prior to 36 Months in Autism Spectrum Disorders
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The present study investigated differences among children with three different patterns of autism symptom onset: regression, plateau, and no loss and no plateau. Cross-sectional data were collected from parents of children aged 3–17 years with an autism spectrum disorder (n = 2,720) who were recruited through a US-based online research database. Parental report of developmental characteristics was assessed through a parent questionnaire, and current autism symptoms were measured via the Social Responsiveness Scale and Social Communication Questionnaire. Multivariate analyses indicated that children with regression had a distinct developmental pattern marked by less delayed early development. However, following regression, these children evinced elevated autism symptom scores and an increased risk for poorer outcomes when compared with the other onset groups.
KeywordsAutism Pervasive developmental disorders Regression Symptom Onset pattern
This research was supported by grants to the last author from Autism Speaks. The funder had no role in determining content. We would like to thank Connie Anderson, Teresa Foden, and Gregory Kalb for their unique contributions to this article.
- American Psychiatric Association (2000). Diagnostic and statistical manual of mental disorders (4th ed., text revision). Washington, DC: American Psychiatric Association.Google Scholar
- Constantino, J., Davis, S., Todd, R., Schindler, M., Gross, M., Brophy, S., et al. (2003). Validation of a brief quantitative measure of autistic traits: Comparison of the Social Responsiveness Scale with the Autism Diagnostic Interview-Revised. Journal of Autism and Developmental Disorders, 33, 427–433.CrossRefPubMedGoogle Scholar
- Hoshino, Y., Kaneko, M., Yashima, Y., Kumashiro, H., Volkmar, F., & Cohen, D. (1987). Clinical features of autistic children with setback course in their infancy. Japanese Journal of Child and Adolescent Psychiatry, 26, 201–212.Google Scholar
- Kanner, L. (1943). Autistic disturbances of affective contact. Nervous Child, 2, 217–250.Google Scholar
- Pine, E., Luby, J., Abbacchi, A., & Constantino, J. N. (2006). Quantitative assessment of autistic symptomatology in preschoolers. Autism: The International Journal of Research and Practice, 10, 344–352.Google Scholar
- World Health Organization (1992). International classification of disease-10, Geneva.Google Scholar