Event Related Potentials in the Understanding of Autism Spectrum Disorders: An Analytical Review

Original Paper

Abstract

In this paper we critically review the literature on the use of event related potentials (ERPs) to elucidate the neural sources of the core deficits in autism. We review auditory and visual ERP studies, and then review the use of ERPs in the investigation of executive function. We conclude that, in autism, impairments likely exist in both low and higher level auditory and visual processing, with prominent impairments in the processing of social stimuli. We also discuss the putative neural circuitry underlying these deficits. As we look to the future, we posit that tremendous insight can be gained by applying ERPs to the definition of endophenotypes, which, in turn, can facilitate early diagnosis and the creation of informed interventions for children with autism.

Keywords

Event related potential (ERP) Autism Auditory processing Visual processing 

Notes

Acknowledgements

The writing of this paper was made possible by support from the Richard David Scott endowment (Nelson), Autism Speaks, Mentored Research Fellowship (Jeste), and the Child Neurology Foundation, Researcher in Training Award (Jeste).

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© Springer Science+Business Media, LLC 2008

Authors and Affiliations

  1. 1.Children’s Hospital BostonHarvard Medical SchoolBostonUSA

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