The Autism Diagnostic Observation Schedule: Revised Algorithms for Improved Diagnostic Validity

  • Katherine Gotham
  • Susan Risi
  • Andrew Pickles
  • Catherine Lord
Original Paper

Abstract

Autism Diagnostic Observation Schedule (ADOS) Modules 1–3 item and domain total distributions were reviewed for 1,630 assessments of children aged 14 months to 16 years with an autism spectrum disorder (ASD) or with heterogeneous non-spectrum disorders. Children were divided by language level and age to yield more homogeneous cells. Items were chosen that best differentiated between diagnoses and were arranged into domains on the basis of multi-factor item-response analysis. Reflecting recent research, the revised algorithm now consists of two new domains, Social Affect and Restricted, Repetitive Behaviors (RRB), combined to one score to which thresholds are applied, resulting in generally improved predictive value.

Keywords

Autism Autism spectrum disorders PDD-NOS Diagnosis 

Copyright information

© Springer Science+Business Media, LLC 2006

Authors and Affiliations

  • Katherine Gotham
    • 1
  • Susan Risi
    • 1
  • Andrew Pickles
    • 2
  • Catherine Lord
    • 1
  1. 1.University of Michigan Autism and Communication Disorders CenterAnn ArborUSA
  2. 2.Division of Epidemiology and Health Science University of Manchester ManchesterUnited Kingdom

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