Two Boys with 47, XXY and Autism

Original Paper

DOI: 10.1007/s10803-006-0211-1

Cite this article as:
Merhar, S.L. & Manning-Courtney, P. J Autism Dev Disord (2007) 37: 840. doi:10.1007/s10803-006-0211-1


Two children with autism and Klinefelter syndrome (KS) (47, XXY) are presented. Both qualify for the diagnosis of autism based on DSM-IV with severely delayed and disordered language, difficulties with social interaction, and a restricted range of interests and activities. Both also have abnormal EEGs, and one patient has had what appear to be clinical seizures. Trials of antiepileptic medications have not been beneficial in either patient. We report the clinical and EEG findings of each patient, and discuss the implications of this combination of disorders.


Autistic spectrum disorders Autism Epilepsy EEG Klinefelter syndrome 

Copyright information

© Springer Science+Business Media, Inc. 2006

Authors and Affiliations

  1. 1.University of Pennsylvania Medical CenterPhiladelphiaUSA
  2. 2.Division of Developmental DisabilitiesCincinnati Children’s Hospital Medical CenterCincinnatiUSA
  3. 3.House Staff DepartmentCincinnati Children’s Hospital Medical CenterCincinnatiUSA

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