Journal of Autism and Developmental Disorders

, Volume 35, Issue 5, pp 645–656 | Cite as

Video Analysis of Sensory-Motor Features in Infants with Fragile X Syndrome at 9–12 Months of Age

  • Grace T. Baranek
  • Cassandra D. Danko
  • Martie L. Skinner
  • Donald B. Jr., Deborah D. Hatton
  • Jane E. Roberts
  • Penny L. Mirrett


This study utilized retrospective video analysis to distinguish sensory-motor patterns in infants with fragile X syndrome (FXS) (n=11) from other infants [i.e., autism (n=11), other developmental delay (n=10), typical (n=11)] at 9–12 months of age. Measures of development, autistic features, and FMRP were assessed at the time of entry into the study. Home videos collected from families were edited and coded with previously validated procedures. Findings revealed a pattern of sensory-motor features (e.g., repetitive leg movements, posturing, less sophistication/repetitive use of objects) associated with FXS, and suggest these infants were most similar to the group of infants with other developmental delays, irrespective of co-existing autistic symptoms later in life. Infant sensory-motor features in the FXS group were more predictive of an early developmental milestone (i.e., age walking) than later, more broad, developmental outcomes, or FMRP. Implications for early identification and differential diagnosis are discussed.


Home movies mental retardation fragile X syndrome (FXS) autism sensorimotor development infancy 



This research was funded in part by U.S. Department of Education, Office of Special Education Programs (Grant #H324C990042). Preliminary data were presented at the Gatlinburg Conference on Research and Theory in Intellectual and Developmental Disabilities, March 2003. The authors express their appreciation to the Carolina Fragile X Project, the participating families, and Fabian David, Michelle Rakes, Kelly Sullivan, Don Trull, and Anne Wheeler for assistance with aspects of video coding and editing.


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Copyright information

© Springer 2005

Authors and Affiliations

  • Grace T. Baranek
    • 1
    • 2
  • Cassandra D. Danko
    • 1
  • Martie L. Skinner
    • 1
  • Donald B. Jr., Deborah D. Hatton
    • 1
  • Jane E. Roberts
    • 1
  • Penny L. Mirrett
    • 1
  1. 1.Division of Occupational Science, Department of Allied Health SciencesUniversity of North Carolina at Chapel HillChapel HillUSA
  2. 2.Division of Occupational Science, Department of Allied Health SciencesUniversity of North Carolina at Chapel HillChapel HillUSA

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