Journal of Autism and Developmental Disorders

, Volume 34, Issue 5, pp 583–586 | Cite as

Brief Report: Autistic Disorder in Three Children with Cytomegalovirus Infection

  • Thayne L. Sweeten
  • David J. Posey
  • Christopher J. McDougle


Previous research has identified a relationship between autistic disorder (autism) and specific congenital infections. Three cases of congenital or perinatal cytomegalovirus (CMV) infection occurring in association with autism are described. Hypothetical mechanisms relating congenital infection, such as CMV, to the development of autism are discussed. A better understanding of the immunologic response to certain congenital infections may provide important information pertaining to the pathophysiology and etiology of autism in vulnerable individuals.

Autism cytomegalovirus congenital infection autoimmune 


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Copyright information

© Springer Science+Business Media, Inc. 2004

Authors and Affiliations

  • Thayne L. Sweeten
    • 1
  • David J. Posey
    • 1
    • 2
  • Christopher J. McDougle
    • 1
    • 2
  1. 1.Department of PsychiatryIndiana University School of Medicine, Psychiatry Building --IndianapolisUSA; James Whitcomb Riley Hospital for Children, Indianapolis, IN, USA
  2. 2.James Whitcomb Riley Hospital for ChildrenIndianapolisUSA

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