Journal of Abnormal Child Psychology

, Volume 40, Issue 5, pp 759–769 | Cite as

Psychopathic Traits and Physiological Responses to Aversive Stimuli in Children Aged 9–11 Years

  • Pan Wang
  • Laura A. Baker
  • Yu Gao
  • Adrian Raine
  • Dora Isabel Lozano
Article

Abstract

Atypical eletrodermal and cardiovascular response patterns in psychopathic individuals are thought to be biological indicators of fearless and disinhibition. This study investigated the relationship between psychopathic traits and these autonomic response patterns using a countdown task in 843 children (aged 9–10 years). Heart rate (HR) and non-specific skin conductance responses (NS-SCRs) were recorded while participants anticipated and reacted to 105 dB signaled or un-signaled white-noise bursts. Using multilevel regression models, both larger HR acceleration and fewer NS-SCR were found to be significantly associated with psychopathic traits during anticipation of signaled white-noise bursts. However, two divergent patterns appeared for HR and SCR: (1) larger HR acceleration was specific to the callousness-disinhibition factor of psychopathic traits while reduced NS-SCR was only associated with the manipulative-deceitfulness factor; (2) the negative association between the manipulative-deceitfulness factor and NS-SCR was only found in boys but not in girls. These findings replicated what has been found in psychopathic adults, suggesting that autonomic deficits present in children at risk may predispose them to later psychopathy. The divergent findings across psychopathic facets and sexes raised the possibility of different etiologies underlying psychopathy, which may in turn suggest multiple treatment strategies for boys and girls.

Keywords

Psychopathy Children Heart rate Skin conductance Countdown 

Notes

Acknowledgments

This study was supported by grants from NIMH to Laura A. Baker (R01 MH58354) and Adrian Raine (K02 MH01114-08). We would like to thank the Southern California Twin Project staff for their assistance in collecting data, and the twins and their families for participation.

References

  1. Arnett, P. A. (1997). Autonomic responsivity in psychopaths: a critical review and theoretical proposal. Clinical Psychology Review, 17(8), 903–936.PubMedCrossRefGoogle Scholar
  2. Baker, L. A., Barton, M., Lozano, D. I., Raine, A., & Fowler, J. H. (2006). The Southern California Twin Register at the University of Southern California: II. Twin Research and Human Genetics: The Official Journal of The International Society for Twin Studies, 9(6), 933–940.Google Scholar
  3. Baker, L. A., Jacobson, K. C., Raine, A., Lozano, D. I., & Bezdjian, S. (2007). Genetic and environmental bases of childhood antisocial behavior: a multi-informant twin study. Journal of Abnormal Psychology, 116(2), 219–235.PubMedCrossRefGoogle Scholar
  4. Beauchaine, T. P., Hong, J., & Marsh, P. (2008). Sex differences in autonomic correlates of conduct problems and aggression. Journal of the American Academy of Child and Adolescent Psychiatry, 47(7), 788–796.PubMedGoogle Scholar
  5. Beauchaine, T. P., Katkin, E. S., Strassberg, Z., & Snarr, J. (2001). Disinhibitory psychopathology in male adolescents: discriminating conduct disorder from attention-deficit/hyperactivity disorder through concurrent assessment of multiple autonomic states. Journal of Abnormal Psychology, 110(4), 610–624.PubMedCrossRefGoogle Scholar
  6. Bechara, A., Tranel, D., Damasio, H., Adolphs, R., Rockland, C., & Damasio, A. R. (1995). Double dissociation of conditioning and declarative knowledge relative to the amygdala and hippocampus in humans. Science, 269(5227), 1115–1118.PubMedCrossRefGoogle Scholar
  7. Bezdjian, S., Raine, A., Baker, L. A., & Lynam, D. R. (2011). Psychopathic personality in children: genetic and environmental contributions. Psychological Medicine, 41(3), 589–600.PubMedCrossRefGoogle Scholar
  8. Blair, R. J. R. (1999). Responsiveness to distress cues in the child with psychopathic tendencies. Personality and Individual Differences, 27(1), 135–145.CrossRefGoogle Scholar
  9. Blom, G. (1958). Statistical estimates and transformed beta-variables. New York: Wiley.Google Scholar
  10. Blonigen, D. M., Hicks, B. M., Krueger, R. F., Patrick, C. J., & Iacono, W. G. (2005). Psychopathic personality traits: heritability and genetic overlap with internalizing and externalizing psychopathology. Psychological Medicine, 35(05), 637–648.PubMedCrossRefGoogle Scholar
  11. Carlson, S. R., & Iacono, W. G. (2006). Heritability of P300 amplitude development from adolescence to adulthood. Psychophysiology, 43(5), 470–480.PubMedCrossRefGoogle Scholar
  12. Farrington, D. P. (2005). The importance of child and adolescent psychopathy. Journal of Abnormal Child Psychology, 33(4), 489–497.PubMedCrossRefGoogle Scholar
  13. Fowles, D. C. (1993). Electrodermal activity and antisocial behavior: Empirical findings and theoretical issues. In J.-C. Roy, W. Boucsein, D. C. Fowles, & J. H. Gruzelier (Eds.), Progress in electrodermal research (pp. 223–237). New York: Plenum Press.CrossRefGoogle Scholar
  14. Frick, P. J., Bodin, S. D., & Barry, C. T. (2000). Psychopathic traits and conduct problems in community and clinic-referred samples of children: further development of the psychopathy screening device. Psychological Assessment, 12(4), 382–393.PubMedCrossRefGoogle Scholar
  15. Frick, P. J., & Hare, R. D. (2001). Antisocial process screening device. Toronto: Multi-Health Systems.Google Scholar
  16. Frick, P. J., & White, S. F. (2008). Research review: the importance of callous-unemotional traits for developmental models of aggressive and antisocial behavior. Journal of Child Psychology and Psychiatry, 49(4), 359–375.PubMedCrossRefGoogle Scholar
  17. Fung, M. T., Raine, A., Loeber, R., Lynam, D. R., Steinhauer, S. R., Venables, P. H., et al. (2005). Reduced electrodermal activity in psychopathy-prone adolescents. Journal of Abnormal Psychology, 114(2), 187–196.PubMedCrossRefGoogle Scholar
  18. Gao, Y., Glenn, A. L., Schug, R. A., Yang, Y., & Raine, A. (2009). The neurobiology of psychopathy: a neurodevelopmental perspective. Canadian Journal of Psychiatry, 54(12), 813–823.Google Scholar
  19. Gao, Y., & Raine, A. (2010). Successful and unsuccessful psychopaths: a neurobiological model. Behavioral Sciences & the Law, 28(2), 194–210.Google Scholar
  20. Hall, J. R., Benning, S. D., & Patrick, C. J. (2004). Criterion-related validity of the three-factor model of psychopathy. Assessment, 11(1), 4–16.PubMedCrossRefGoogle Scholar
  21. Hare, R. D. (1978). Electrodermal and cardiovascular correlates of psychopathy. In R. D. Hare & D. Schalling (Eds.), Psychopathic behavior: approaches to research (pp. 107–143). Chichester: Wiley.Google Scholar
  22. Hare, R. D. (1982). Psychopathy and physiological activity during anticipation of an aversive stimulus in a distraction paradigm. Psychophysiology, 19(3), 266–271.PubMedCrossRefGoogle Scholar
  23. Hare, R. D. (1991). Manual for the revised psychopathy checklist. Toronto: Multi-Health Systems.Google Scholar
  24. Hare, R. D., & Craigen, D. (1974). Psychopathy and physiological activity in a mixed motive game situation. Psychophysiology, 11(2), 197–206.PubMedCrossRefGoogle Scholar
  25. Hare, R. D., Frazelle, J., & Cox, D. N. (1978). Psychopathy and physiological responses to threat of an aversive stimulus. Psychophysiology, 15(2), 165–172.PubMedCrossRefGoogle Scholar
  26. Hare, R. D., & Neumann, C. S. (2006). The PCL-R assessment of psychopathy: Development, structural properties, and new directions. In C. J. Patrick (Ed.), Handbook of psychopathy (pp. 58–88). New York: Guilford Press.Google Scholar
  27. Herpertz, S. C., Werth, U., Lukas, G., Qunaibi, M., Schuerkens, A., Kunert, H. J., et al. (2001). Emotion in criminal offenders with psychopathy and borderline personality disorder. Archives of General Psychiatry, 58(8), 737–745.PubMedCrossRefGoogle Scholar
  28. Hicks, B. M., & Patrick, C. J. (2006). Psychopathy and negative emotionality: analyses of suppressor effects reveal distinct relations with emotional distress, fearfulness, and anger-hostility. Journal of Abnormal Psychology, 115(2), 276–287.PubMedCrossRefGoogle Scholar
  29. Hugdahl, K. (1995). Psychophysiology: the mind-body perspective. Cambridge: Harvard University Press.Google Scholar
  30. Isen, J., Raine, A., Baker, L., Dawson, M., Bezdjian, S., & Lozano, D. I. (2010). Sex-specific association between psychopathic traits and electrodermal reactivity in children. Journal of Abnormal Psychology, 119(1), 216.PubMedCrossRefGoogle Scholar
  31. Kraemer, H. C., Measelle, J. R., Ablow, J. C., Essex, M. J., Boyce, W. T., & Kupfer, D. J. (2003). A new approach to integrating data from multiple informants in psychiatric assessment and research: mixing and matching contexts and perspectives. The American Journal of Psychiatry, 160(9), 1566–1577.PubMedCrossRefGoogle Scholar
  32. LaBar, K. S., LeDoux, J. E., Spencer, D. D., & Phelps, E. A. (1995). Impaired fear conditioning following unilateral temporal lobectomy in humans. The Journal of Neuroscience, 15(10), 6846–6855.PubMedGoogle Scholar
  33. Lorber, M. F. (2004). Psychophysiology of aggression, psychopathy, and conduct problems: a meta-analysis. Psychological Bulletin, 130(4), 531–552.PubMedCrossRefGoogle Scholar
  34. Lynam, D. R. (1997). Pursuing the psychopath: capturing the fledgling psychopath in a nomological net. Journal of Abnormal Psychology, 106(3), 425–438.PubMedCrossRefGoogle Scholar
  35. McArdle, J. J. (2006). Latent curve analyses of longitudinal twin data using a mixed-effects biometric approach. Twin Research and Human Genetics, 9(3), 343–359.PubMedCrossRefGoogle Scholar
  36. Ogloff, J. R. P., & Wong, S. (1990). Electrodermal and cardiovascular evidence of a coping response in psychopaths. Criminal Justice and Behavior, 17(2), 231–245.CrossRefGoogle Scholar
  37. Patrick, C. J. (1994). Emotion and psychopathy: startling new insights. Psychophysiology, 31(4), 319–330.PubMedCrossRefGoogle Scholar
  38. Patrick, C. J., & Bernat, E. M. (2010). Neuroscientific foundations of psychopathology. In R. F. K. T. Millon & E. Simonsen (Eds.), Contemporary directions in psychopathology: scientific foundations of the DSM-V and ICD-II (pp. 419–452). New York: Guilford Press.Google Scholar
  39. Patrick, C. J., Fowles, D. C., & Krueger, R. F. (2009). Triarchic conceptualization of psychopathy: developmental origins of disinhibition, boldness, and meanness. Development and Psychopathology, 21, 913–938.PubMedCrossRefGoogle Scholar
  40. Patrick, C. J., Hicks, B. M., Nichol, P. E., & Krueger, R. F. (2007). A bifactor approach to modeling the structure of the psychopathy checklist-revised. Journal of Personality Disorders, 21(2), 118–141.PubMedCrossRefGoogle Scholar
  41. Porges, S. W. (1995). Orienting in a defensive world: mammalian modifications of our evolutionary heritage. A polyvagal theory. Psychophysiology, 32(4), 301–318.PubMedCrossRefGoogle Scholar
  42. Raine, A. (1997). The psychopathology of crime: criminal behavior as a clinical disorder. London: Academic.Google Scholar
  43. Rutherford, M. J., Alterman, A. I., Cacciola, J. S., & Snider, E. C. (1995). Gender differences in diagnosing antisocial personality disorder in methadone patients. The American Journal of Psychiatry, 152(9), 1309–1316.PubMedGoogle Scholar
  44. Somsen, R. J. M., Jennings, J. R., & Van der Molen, M. W. (2004). The cardiac cycle time effect revisited: temporal dynamics of the central vagal modulation of heart rate in human reaction time tasks. Psychophysiology, 41(6), 941–953.PubMedCrossRefGoogle Scholar
  45. van Beijsterveldt, C. E. M., van Baal, G. C. M., Molenaar, P. C. M., Boomsma, D. I., & de Geus, E. J. C. (2001). Stability of genetic and environmental influences on P300 amplitude: a longitudinal study in adolescent twins. Behavior Genetics, 31(6), 533–543.PubMedCrossRefGoogle Scholar
  46. Venables, P. H., & Mitchell, D. A. (1996). The effects of age, sex and time of testing on skin conductance activity. Biological Psychology, 43(2), 87–101.PubMedCrossRefGoogle Scholar
  47. Verona, E., Patrick, C. J., Curtin, J. J., Bradley, M. M., & Lang, P. J. (2004). Psychopathy and physiological response to emotionally evocative sounds. Journal of Abnormal Psychology, 113(1), 99–108.PubMedCrossRefGoogle Scholar
  48. Yoon, H. H., Iacono, W. G., Malone, S. M., & McGue, M. (2006). Using the brain P300 response to identify novel phenotypes reflecting genetic vulnerability for adolescent substance misuse. Addictive Behaviors, 31(6), 1067–1087.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, LLC 2012

Authors and Affiliations

  • Pan Wang
    • 1
  • Laura A. Baker
    • 1
  • Yu Gao
    • 2
  • Adrian Raine
    • 3
  • Dora Isabel Lozano
    • 4
  1. 1.Department of Psychology (SGM 501)University of Southern CaliforniaLos AngelesUSA
  2. 2.Department of PsychologyBrooklyn College of the City University of New YorkBrooklynUSA
  3. 3.Departments of Criminology, Psychiatry, and PsychologyUniversity of PennsylvaniaPhiladelphiaUSA
  4. 4.Universidad Autónoma de Ciudad JuárezChihuahuaMexico

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