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Medium-term clinical outcomes following Xen45 device implantation

  • Aitor Fernández-García
  • Ying Zhou
  • Mercedes García-Alonso
  • Henry D. Andrango
  • Francisco Poyales
  • Nuria GarzónEmail author
Original Paper
  • 31 Downloads

Abstract

Purpose

To evaluate medium-term clinical outcomes with microstent XEN® 45 Gel Stent (Allergan Dublin, Ireland) for treatment of primary open-angle glaucoma (POAG).

Material and methods

This is a retrospective, descriptive and observational study involving 93 eyes from 63 patients who had undergone POAG surgery with a XEN® 45 Gel Stent implantation and had been followed up and controlled between 12 and 36 months.

Results

IOP dropped from 18.23 ± 5.00 mmHg pre-op to 14.16 ± 2.14, 14.47 ± 2.16 and 14.63 ± 1.91 at 1, 2 and 3 years after surgery (p = 0.000, 0.000 and 0.001) consecutively. Mean number of medications dropped from 1.87 ± 0.94 preoperatively to 0.31 ± 0.69, 0.34 ± 0.63 and 1.00 ± 0.88 (p = 0.000, 0.000 and 0.017) at 12, 24 and 36 months. Mean visual field deviation values never turned out to be significant for any of the follow-up visit data. A total of 94.6% of the surgical procedures turned out to be complication-free. In one surgery, the procedure failed and 18 months later other device was implanted.

Conclusion

POAG surgical procedures with XEN® 45 Gel Stent implants are a safe and effective treatment approach.

Keywords

Glaucoma MIGS Xen45 

Notes

Acknowledgements

This study was supported by Allergan via an independent and unrestricted research grant. Neither honoraria nor payments were made for authorship. It should be noted that Allergan S.A. was not involved in the development of the study.

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

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Copyright information

© Springer Nature B.V. 2019

Authors and Affiliations

  1. 1.IOA MadridMadridSpain
  2. 2.Optometry and Vision Department, Faculty of Optics and OptometryComplutense University of MadridMadridSpain

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