International Ophthalmology

, Volume 39, Issue 11, pp 2569–2574 | Cite as

Comparison of Samfilcon A and Lotrafilcon B silicone hydrogel bandage contact lenses in reducing postoperative pain and accelerating re-epithelialization after photorefractive keratectomy

  • Erdem YukselEmail author
  • Kemal Ozulken
  • Mehmet Murat Uzel
  • Ayse Guzin Taslipinar Uzel
  • Semih Aydoğan
Original Paper



To compare the efficacy of Samfilcon A and Lotrafilcon B bandage contact lenses after photorefractive keratectomy (PRK).


In this study, patients with bilateral PRK were assigned for the fitting of Lotrafilcon B lens and Samfilcon A lens. The patients were examined on the day of surgery and on postoperative days 1, 2 and 3. Slit biomicroscopy was performed to assess epithelial defect size in the postoperative examinations. The subjective evaluation of pain and visual symptoms was recorded on postoperative days 1, 2 and 3.


Analysis was made of 68 eyes of 34 patients who fulfilled the criteria and had PRK for correction of low to moderate myopia/astigmatism. On postoperative days 1 and 2, pain and epiphora scores were significantly lower in eyes with Samfilcon A lens (p < 0.001 for all), and on postoperative day 3, the differences were not significant (p = 0.414 and p = 0.180, respectively). There was no significant difference between the two lenses in respect of the levels of photophobia. The difference in epithelial defect size was statistically lower in eyes with Samfilcon A lens compared to Lotrafilcon B on day 1 (16.89 mm2 vs. 21.07 mm2; p = 0.003) and day 2 (1.49 mm2 vs. 2.46 mm2; p < 0.001). The difference was not significant on day 3. (0.05 mm2 vs. 0.05 mm2; p = 1.000).


The Samfilcon A lens is superior to the Lotrafilcon B lens in reducing postoperative pain and accelerating re-epithelialization.


Photorefractive keratectomy Bandage contact lens Samfilcon A Lotrafilcon B Epithelial defect size 


Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.


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Copyright information

© Springer Nature B.V. 2019

Authors and Affiliations

  1. 1.Ophthalmology Department, Faculty of MedicineKastamonu UniversityKastamonuTurkey
  2. 2.Ophthalmology DepartmentTobb-Etu University HospitalAnkaraTurkey
  3. 3.Ophthalmology DepartmentAfyonkarahisar State HospitalAfyonkarahisarTurkey
  4. 4.Ophthalmology DepartmentAfyonkarahisar Sandıklı State HospitalAfyonkarahisarTurkey
  5. 5.Ophthalmology DepartmentWorld Eye HospitalAnkaraTurkey

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