Topographic indices and pachymetry in healthy adolescents obtained with Sirius topographer
- 90 Downloads
To determine the normal values for the Sirius corneal topography, of some topographic indices and corneal pachymetry, in a healthy young adolescent population.
A total of 176 students (mean age 12.95 ± 0.82 years) took part in this study. 352 eyes were imaged through Sirius topographer. Anterior and posterior meridians, mean pupillary power, central corneal thickness, minimum corneal thickness, and anterior and posterior asymmetry indices were analyzed. Correlations between corneal parameters and differences between anterior and posterior corneal surfaces were evaluated.
Average anterior meridian was 43.37 D (± 1.46); average posterior meridian was 6.16 D (± 0.24); central corneal thickness was 550.81 ± 29.88 micron, minimum corneal thickness was 547.36 ± 29.93 micron; mean pupillary power was 42.95 ± 1.46 D, SIf was − 0.035 ± 0.46, and SIb was 0.012 ± 0.091. Anterior and posterior corneal curvatures correlated negatively with MPP (r = − 0.99; p = 0.000 and r = − 0.85 p = 0.000, respectively). Anterior curvature correlated positively with posterior curvature (r = 0.891; p = 0.000). Positive correlations were found for SIf and SIb (r = 0.58; p = 0.000). Negative correlations were found for SIf and corneal pachymetry (r = − 0.23; p = 0.000) and for SIb and corneal pachymetry (r = − 0.19; p = 0.012). The difference between anterior meridian average and posterior meridian average was 1.29 ± 0.12 and was significative (p < 0.001). No differences between genders were found.
These results provide normal standards for corneal values in adolescents and could represent a useful tool for future comparative studies in this age-group population.
KeywordsCorneal topography Sirius topographer Adolescents Topography indices
We are grateful to Dr. Ruth Dureghello (President of the Jewish Community of Rome) for allowing us to carry out this observational study and Prof. Angelo Sacerdoti (Middle School Director), Rav Prof. Benedetto Carucci (High School Director), and all the assistant personnel that collaborated on this observational study.
MC and AM were supported by the Italian Ministry of Health and Fondazione Roma. Fondazione Roma and Italian Ministry of Health provided financial support in the form of, respectively, intramural (Fondazione Roma) and current research (MoH) funding. The sponsor had no role in the design or conduct of this research.
Compliance with ethical standards
Conflict of interest
EC, MC, RS, and AM certified that they have no affiliations with or involvement in any organization or entity with any financial interest (such as honoraria, educational grants, participation in speakers’ bureaus, membership, employment, consultancies, stock ownership, or other equity interest, and expert testimony of patent-licensing arrangements), or non-financial interest (such as personal or professional relationships, affiliations, knowledge or beliefs) in the subject matter or materials discussed in this manuscript. Gabriele Vestri is a CSO employee. He declares no fees for the present study.
All procedures performed in this study were in accordance with the ethical standards of the Institutional Review Board of the Israelitic Hospital of Rome and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Informed consent was obtained from all individual participants included in the study.
- 8.Feder RS, Neems LC (2017) Non inflammatory ectatic disordes. Chapter 72. In: Mannis MJ, Holland EJ (eds) Cornea fundamentals, diagnosis and management (e-book), vol 4. Elsevier, New York, p 821Google Scholar
- 10.Rabinowitz YS (2007) Diagnosing keratoconus and patients at risk. Cat Refract Surg Today. 2007 May. http://crstoday.com/2007/05/CRST0507_15.php