Advertisement

International Ophthalmology

, Volume 38, Issue 6, pp 2321–2325 | Cite as

Glaucoma following childhood cataract surgery: the South India experience

  • Ifeoma EzegwuiEmail author
  • Meenakshi Ravindran
  • Neelam Pawar
  • Fathima Allapitchai
  • Ramakrishnan Rengappa
  • R. Ramalakshmi Raman
Original Paper
  • 84 Downloads

Abstract

Purpose

To determine the characteristics and risk factors for the development of glaucoma after cataract surgery in children seen at a major referral tertiary eye centre in South India.

Methods

This is a retrospective review of the medical records of consecutive patients seen at the glaucoma/paediatric eye clinic of the centre, with a diagnosis of glaucoma secondary to aphakia/pseudophakia over a 5-year period.

Results

There were 21 eyes of 14 children that developed glaucoma and 23 eyes of 12 children were selected as control. The mean age (standard deviation SD) at the time of cataract surgery for the glaucoma group was 7.4 (± 10.1) months and 39.13 (± 41.2) months for the control. The mean follow-up (SD) period was 114.29 (± 61.9) months and 97.61 (± 43.5) months for the glaucoma and control, respectively. The mean duration from cataract surgery to onset of glaucoma was 81.19 (± 52.4) months (median 66 months, range 21–172 months). Multivariate analysis detected age at surgery younger than 12 months (OR 10.45, 95%CI 1.76–62.03, p = 0.010) and ocular anomalies mainly microcornea (OR 7.11, 95%CI 1.14–44.46, p = 0.036) as risk factors for development of glaucoma after paediatric cataract surgery.

Conclusion

Glaucoma can develop several years after childhood cataract surgery. Surgery in the first year of life and microcornea are risk factors for the development of glaucoma post-surgery. Signs of glaucoma should specifically be looked for during follow-up visits.

Keywords

Paediatric cataract surgery Glaucoma in aphakia/pseudophakia Risk factors for glaucoma in aphakia/pseudophakia South India 

Notes

Compliance with ethical standards

Conflict of interest

The authors declared that they have no conflict of interest.

References

  1. 1.
    Kirwan C, O’Keefe M (2006) Paediatricaphakic glaucoma. Acta Ophthalmol Scand 84:734–739CrossRefGoogle Scholar
  2. 2.
    Al-Dahmash S, Khan AO (2010) Paediatric pseudophakic glaucoma following surgery for isolated childhood cataract. Ophthalmic Surg Lasers Imaging 41:463–466CrossRefGoogle Scholar
  3. 3.
    Wong IB, Sukthankar ND, Cortina-Borja M, Nischal KK (2009) Incidence of early-onset glaucoma after infant cataract extraction with and without intraocular lens implantation. Br J Ophthalmol 93:1200–1203CrossRefGoogle Scholar
  4. 4.
    Shenoy BH, Mittal V, Gupta A, Sachdeva V, Kekunnaya R (2015) Complications and visual outcomes after secondary intraocular lens implantation in children. Am J Ophthalmol 159:720–726CrossRefGoogle Scholar
  5. 5.
    Nagamoto T, Oshika T, Fujikodo T, Ishibashi T, Sato M, Kondo M, Kurosaka D et al (2016) Surgical outcomes of congenital and developmental cataract in Japan. Jpn J Ophthalmol Mar, E-pub ahead of printGoogle Scholar
  6. 6.
    Freedman SF, Lynn MJ, Beck AD, Bothun ED, Orge FH, Lambert SR (2015) Glaucoma related adverse events in the first five years after unilateral cataract removal in the Infant Aphakia Treatment Study. JAMA Ophthalmol 133:907–914CrossRefGoogle Scholar
  7. 7.
    Swamy BN, Billson F, Martin F, Donaldson C, Hing S, Smith JEH (2007) Secondary glaucoma after paediatric cataract surgery. Br J Ophthalmol 91:1627–1630CrossRefGoogle Scholar
  8. 8.
    Mandal AK, Netland PA (2014) Glaucoma in aphakia and pseudophakia after congenital cataract surgery. Indian J Ophthalmol 52:185Google Scholar
  9. 9.
    Levin AV (2007) Aphakic glaucoma: a never-ending story? Br J Ophthalmol 91:1574–1575CrossRefGoogle Scholar
  10. 10.
    Wilson ME, Pandy SK, Thakur J (2003) Paediatric cataract blindness in the developing world: surgical techniques and intraocular lenses in the new millennium. Br J Ophthalmol 87:14–19CrossRefGoogle Scholar
  11. 11.
    Lambert SR (2016) The timing of surgery for congenital cataracts—minimizing the risk of glaucoma following cataract surgery while optimizing the visual outcome. J AAPOS 20:191–192CrossRefGoogle Scholar
  12. 12.
    El Shakankiri NM, Lotfy Bayoumi NH (2016) Delayed surgery for best surgical outcomes. J AAPOS 20:191–193CrossRefGoogle Scholar
  13. 13.
    Michaelides M, Bunce C, Adams GGW (2007) Glaucoma following congenital cataract surgery—the role of early surgery and posterior capsulotomy. BMC Ophthalmol 7:13CrossRefGoogle Scholar
  14. 14.
    Mills MD, Robb RM (1994) Glaucoma following childhood cataract surgery. J Pediatr Ophthalmol Strabismus 31:355–360PubMedGoogle Scholar
  15. 15.
    Papadopoulos M, Khaw PT (2003) Meeting the challenge of glaucoma after paediatric cataract surgery. Eye 17:1–2CrossRefGoogle Scholar
  16. 16.
    Koc F, Kangi S, Biglan AW, Chu CT, Davis JS (2006) The aetiology in paediatric aphakic glaucoma. Eye 20:1360–1365CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media B.V. 2017

Authors and Affiliations

  • Ifeoma Ezegwui
    • 1
    • 2
    Email author
  • Meenakshi Ravindran
    • 1
  • Neelam Pawar
    • 1
  • Fathima Allapitchai
    • 1
  • Ramakrishnan Rengappa
    • 3
  • R. Ramalakshmi Raman
    • 4
  1. 1.Paediatric Ophthalmology and Adult Strabismus ServicesAravind Eye HospitalTirunelveliIndia
  2. 2.Paediatric Ophthalmology and Strabismus Unit, Department of Ophthalmology, College of MedicineUniversity of NigeriaEnuguNigeria
  3. 3.Glaucoma ServicesAravind Eye HospitalTirunelveliIndia
  4. 4.Aravind Eye HospitalTirunelveliIndia

Personalised recommendations