International Ophthalmology

, Volume 34, Issue 3, pp 679–684 | Cite as

Recurrent Vogt–Koyanagi–Harada disease with sensorineural hearing loss and choroidal thickening

  • Akihiro Ishibazawa
  • Reiko Kinouchi
  • Yoshiro Minami
  • Akihiro Katada
  • Akitoshi Yoshida
Case Report


We report a case of Vogt–Koyanagi–Harada (VKH) disease that recurred with sensorineural hearing loss and choroidal thickening. We measured the choroidal thickness using enhanced-depth imaging optical coherence tomography (EDI-OCT) in a patient with VKH during corticosteroid-tapering therapy. A 71-year-old male presented with fever, headache, and anorthopia associated with wavy choroidal folds and a serous retinal detachment (SRD). The EDI-OCT images showed choroidal thickening (>600 μm at the subfovea), and he was diagnosed with VKH disease. After treatment with pulsed intravenous methylprednisolone, the choroidal folds and SRD resolved and the choroidal thickness decreased. About 6 months after subsequent treatment with an oral corticosteroid started, headache, tinnitus, and sensorineural hearing loss developed, and increased choroidal thickness was observed without other evidence of increased ocular inflammation. A high-dose corticosteroid was injected and tapered, and the sensorineural hearing loss improved immediately and the choroidal thickness decreased. In the current case, sensorineural hearing loss occurred with recurrent VKH disease; however, there were no ocular inflammatory signs except for rebound choroidal thickening. Measuring the choroidal thickness using EDI-OCT can sensitively identify recurrent VKH disease.


Vogt–Koyanagi–Harada disease Choroidal thickness Enhanced-depth imaging optical coherence tomography Sensorineural hearing loss 



The authors have no financial interest in any aspect of this report. Supported by a Grant-in-Aid for Young Scientists (B) 23791956 and 25861608 (A.I.), and Challenging Exploratory Research 23659803 (R.K.) from the Ministry of Education, Science, and Culture, Tokyo, Japan.


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Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  • Akihiro Ishibazawa
    • 1
    • 2
    • 4
  • Reiko Kinouchi
    • 1
    • 3
  • Yoshiro Minami
    • 1
    • 4
  • Akihiro Katada
    • 5
  • Akitoshi Yoshida
    • 1
  1. 1.Department of OphthalmologyAsahikawa Medical UniversityAsahikawaJapan
  2. 2.Department of Ocular Tissue EngineeringAsahikawa Medical UniversityAsahikawaJapan
  3. 3.Department of Medicine and Engineering Combined ResearchAsahikawa Medical UniversityAsahikawaJapan
  4. 4.Nayoro City General HospitalNayoroJapan
  5. 5.Department of Otolaryngology, Head and Neck SurgeryAsahikawa Medical UniversityAsahikawaJapan

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