Advertisement

International Ophthalmology

, Volume 34, Issue 2, pp 269–275 | Cite as

Assessment of ocular hemodynamics after laser in situ keratomileusis using color Doppler imaging

  • Waleed Abu Samera
  • Maha Shahin
  • Hatem El-Awady
  • Ashraf Abd El-Rahman
  • Nahed El-Toukhy
Original Paper

Abstract

To investigate ocular blood flow changes in healthy myopic patients following laser in situ keratomileusis (LASIK) using color Doppler imaging. Sixteen eyes of 16 myopic patients were studied. LASIK was performed and intraocular pressure was raised to levels ≥65 mmHg. Color Doppler images were obtained to study the ophthalmic and central retinal arteries preoperatively and postoperatively at 1 day, 1 week, and 1 month. There was no significant correlation between patient age and preoperative ocular blood flow parameters. A significant positive correlation between the degree of myopia and the peak systolic volume of the ophthalmic artery (r = 0.6, P = 0.01) was found. A highly significant decrease in the peak systolic volume and end-diastolic volume with an increase in the resistive index of both arteries (P < 0.005) was seen at 1 day and 1 week postoperatively. There was no significant difference between the preoperative and postoperative data 1 month after the procedure. The findings of this study show temporary alterations in ocular blood flow parameters after LASIK. LASIK is an increasingly common lifestyle procedure and further studies on larger groups are still recommended.

Keywords

CDI LASIK Ocular hemodynamics Refractive surgery 

References

  1. 1.
    Pallikaris IG, Siganos DS (1994) Excimer laser in situ keratomileusis and photorefractive keratectomy for correction of high myopia. J Refract Corneal Surg 10:498–510PubMedGoogle Scholar
  2. 2.
    Knorz MC, Liermann A, Seiberth V, Steiner H, Wiesinger B (1996) Laser in situ keratomileusis to correct myopia of -6.00 to -29.00 diopters. J Refract Surg 12:575–584PubMedGoogle Scholar
  3. 3.
    Fraenkel GE, Webber SK, Sutton GL, Lawless MA, Rogers CM (1999) Toric laser in situ keratomileusis for myopic astigmatism using an ablatable mask. J Refract Surg 15:111–117PubMedGoogle Scholar
  4. 4.
    Pallikaris I, Siganos D (1997) LASIK complications management. In: Talamo JH, Krueger RR (eds) The excimer manual: a clinician’s guide to excimer laser surgery. Little, Brown and Company Inc., Boston, pp 227–243Google Scholar
  5. 5.
    Bushkey DM, Parmley VC, Paglen P (2000) Visual field defect associated with laser in situ keratomileusis. Am J Ophthalmol 129:668–671CrossRefGoogle Scholar
  6. 6.
    Lee AG, Kohnen T, Ebner R, Bennett JL, Miller NR, Carlow TJ, Koch DD (2000) Optic neuropathy associated with laser in situ keratomileusis. J Cataract Refract Surg 26:1581–1584CrossRefPubMedGoogle Scholar
  7. 7.
    Cameron BD, Saffra NA, Strominger MB (2001) Laser in situ keratomileusis-induced optic neuropathy. Ophthalmology 108:660–665CrossRefPubMedGoogle Scholar
  8. 8.
    Williamson TH, Harris A (1994) Ocular blood flow measurement. Br J Ophthalmol 78:939–945PubMedCentralCrossRefPubMedGoogle Scholar
  9. 9.
    Harris A, Williamson TH, Martin B, Shoemaker JA, Sergott RC, Spaeth GL, Katz JL (1995) Test/Retest reproducibility of color Doppler imaging assessment of blood flow velocity in orbital vessels. J Glaucoma 4:281–286PubMedGoogle Scholar
  10. 10.
    Riva CE, Titze P, Hero M, Petrig BL (1997) Effect of acute decrease of perfusion pressure on choroidal blood flow in humans. Invest Ophthalmol Vis Sci 38:1752–1760PubMedGoogle Scholar
  11. 11.
    Haefliger IO, Meyer P, Flammer J, Luscher TF (1994) The vascular endothelium as a regulator of the ocular circulation: a new concept in ophthalmology? Surv Ophthalmol 39:123–132CrossRefPubMedGoogle Scholar
  12. 12.
    Pournaras CJ, Logean E, Riva CE, Petrig BL, Chamot SR, Coscas G, Soubrane G (2006) Regulation of subfoveal choroidal blood flow in age-related macular degeneration. Invest Ophthalmol Vis Sci 47(4):1581–1586CrossRefPubMedGoogle Scholar
  13. 13.
    Schocket LS, Brucker AJ, Niknam RM, Grunwald JE, DuPont J, Brucker AJ (2004) Foveolar choroidal hemodynamics in proliferative diabetic retinopathy. Int Ophthalmol 25(2):89–94CrossRefPubMedGoogle Scholar
  14. 14.
    Dallinger S, Findl O, Strenn K, Eichler HG, Wolzt M, Schmetterer L (1998) Age dependence of choroidal blood flow. J Am Geriatr Soc 46(4):484–487PubMedGoogle Scholar
  15. 15.
    Lam AK, Chan ST, Chan H, Chan B (2003) The effect of age on ocular blood supply determined by pulsatile ocular blood flow and color Doppler ultrasonography. Optom Vis Sci 80(4):305–311CrossRefPubMedGoogle Scholar
  16. 16.
    Niknam RM, Schocket LS, Metelitsina T, DuPont JC, Grunwald JE (2004) Effect of hypertension on foveolar choroidal haemodynamics. Br J Ophthalmol 88(10):1263–1265PubMedCentralCrossRefPubMedGoogle Scholar
  17. 17.
    Straubhaar M, Orgul S, Gugleta K, Schötzau A, Erb C, Flammer J (2000) Choroidal laser Doppler flowmetry in healthy subjects. Arch Ophthalmol 118(2):211–215CrossRefPubMedGoogle Scholar
  18. 18.
    Dimitrova G, Tamaki Y, Kato S, Nagahara M (2002) Retrobulbar circulation in myopic patients with or without myopic choroidal neovascularisation. Br J Ophthalmol 86(7):771–773PubMedCentralCrossRefPubMedGoogle Scholar
  19. 19.
    Karczewicz D, Modrzejewska M (2004) Blood flow in eye arteries assessed by Doppler ultrasound in patients with myopia. Klin Oczna 106(1–2 Suppl):211–213PubMedGoogle Scholar
  20. 20.
    Akyol N, Kukner AS, Ozdemir T, Esmeriligil S (1996) Choroidal and retinal blood flow changes in degenerative myopia. Can J Ophthalmol 31(3):113–119PubMedGoogle Scholar
  21. 21.
    Karczewicz D (1987) Study of the vascular system of the eyes in high myopia. Ann Acad Med Stetin 33:229–259PubMedGoogle Scholar
  22. 22.
    Yang Q, Shen J, Guo W, Wen J, Wang Z, Yu D (2011) Effect of acute intraocular pressure elevation on blood flow velocity and resistance in the rabbit ophthalmic artery. Vet Ophthalmol 14:353–357CrossRefPubMedGoogle Scholar
  23. 23.
    Luna JD, Artal MN, Reviglio VE, Pelizzari M, Diaz H, Juarez CP (2001) Vitreoretinal alterations following laser in situ keratomileusis: clinical and experimental studies. Graefes Arch Clin Exp Ophthalmol 239:416–423CrossRefPubMedGoogle Scholar
  24. 24.
    Ozdamar A, Ocakoglu O (2003) Optic nerve head blood flow using scanning laser Doppler flowmetry after laser in situ keratomileusis. J Refract Surg 19:433–437PubMedGoogle Scholar

Copyright information

© Springer Science+Business Media Dordrecht 2013

Authors and Affiliations

  • Waleed Abu Samera
    • 1
  • Maha Shahin
    • 1
  • Hatem El-Awady
    • 1
  • Ashraf Abd El-Rahman
    • 2
  • Nahed El-Toukhy
    • 2
  1. 1.Ophthalmology DepartmentFaculty of Medicine, Mansoura UniversityMansouraEgypt
  2. 2.Radiology DepartmentFaculty of Medicine, Mansoura UniversityMansouraEgypt

Personalised recommendations