Photodynamic therapy for unilateral idiopathic peripapillary choroidal neovascularization in a child
- 113 Downloads
- 2 Citations
Abstract
A 10-year-old girl presented with visual loss in her right eye. Best-corrected visual acuity was 20/50 in the right eye and 20/20 in the left eye. Dilated funduscopic examination revealed a yellowish elevated lesion near the optic disc with macular edema and hemorrhage on the inferotemporal vascular arcade in the right eye. Fluorescein angiography showed a hyperfluorescent lesion consistent with choroidal neovascularization (CNV) and optical coherence tomography (OCT) showed a peripapillary lesion with subretinal fluid elevating the neurosensory retina in the macular area. With a diagnosis of unilateral idiopathic peripapillary CNV, the patient underwent photodynamic therapy (PDT) with verteporfin. At the four month follow-up, visual acuity increased to 20/25 and OCT showed peripapillary scar formation and total resolution of the subretinal fluid. At the one year follow-up, visual acuity and fundus were stable without recurrence of the lesion. PDT for peripapillary CNV in children has not previously been reported. Although it seems to be a favorable treatment option for peripapillary lesions, there is a lack of knowledge about long-term follow-up in pediatric cases.
Keywords
Children Choroidal neovascularization Idiopathic Peripapillary Photodynamic therapyReferences
- 1.Bernstein PS, Horn RS (2008) Verteporfin photodynamic therapy involving the optic nerve for peripapillary choroidal neovascularization. Retina 28(1):81–84PubMedCrossRefGoogle Scholar
- 2.Browning DJ, Fraser CM (2005) Ocular conditions associated with peripapillary subretinal neovascularization, their relative frequencies, and associated outcomes. Ophthalmology 112(6):1054–1061PubMedCrossRefGoogle Scholar
- 3.Mauget-Faÿsse M, Mimoun G, Ruiz-Moreno JM, Quaranta-El Maftouhi M, De Laey JJ, Postelmans L, Soubrane G, Defauchy M, Leys A (2006) Verteporfin photodynamic therapy for choroidal neovascularization associated with toxoplasmic retinochoroiditis. Retina 26(4):396–403PubMedCrossRefGoogle Scholar
- 4.Lipski A, Bornfeld N, Jurklies B (2008) Photodynamic therapy with verteporfin in paediatric and young adult patients: long-term treatment results of choroidal neovascularisations. Br J Ophthalmol 92(5):655–660PubMedCrossRefGoogle Scholar
- 5.Rich R, Vanderveldt S, Berrocal AM, Mavrofrides EC, Murray TG, Gregori N (2009) Treatment of choroidal neovascularization associated with Best’s disease in children. J Pediatr Ophthalmol Strabismus 46(5):306–311PubMedCrossRefGoogle Scholar
- 6.Brown SM, Del Monte MA (1996) Choroidal neovascular membrane associated with optic nerve head drusen in a child. Am J Ophthalmol 121(2):215–217PubMedGoogle Scholar
- 7.Lee EJ, Mavrikakis I, Fong K, Casswell AG (2006) Primary peripapillary membrane in an 8-year-old boy. Eye 20(3):379–380PubMedCrossRefGoogle Scholar
- 8.Giovannini A, Neri P, Mercanti L, Bruè C (2007) Photodynamic treatment versus photodynamic treatment associated with systemic steroids for idiopathic choroidal neovascularisation. Br J Ophthalmol 91(5):620–623PubMedCrossRefGoogle Scholar