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International Ophthalmology

, Volume 30, Issue 5, pp 559–565 | Cite as

Clinical features and prognosis of herpetic anterior uveitis: a retrospective study of 111 cases

  • Ilknur Tugal-Tutkun
  • Berna Ötük-Yasar
  • Emre Altinkurt
Original Paper

Abstract

To describe the clinical features and outcomes in patients with herpetic anterior uveitis. We reviewed the records of 111 patients with a clinical diagnosis of herpetic anterior uveitis seen at the Department of Ophthalmology, Istanbul Faculty of Medicine, from January 1996 to December 2006. Demographic and clinical features, recurrence rate, and visual outcome were analyzed. Fifty patients were male, 61 were female. Mean age at presentation was 39.2 ± 16.5 (6–74) years. Three atopic patients had bilateral involvement. Twelve patients had active or a past episode of herpes zoster ophthalmicus. Ocular findings were granulamatous anterior uveitis (93%), active keratitis or corneal scars (57%), elevated intraocular pressure (51%), iris atrophy (48%), distorted pupil (25%), and posterior synechiae (26%). Secondary glaucoma developed in two patients. None of the patients had posterior segment complications. The recurrence rate was 0.45/person-year. Topical corticosteroids and oral antiviral therapy were administered to all patients during active episodes. Long-term prophylactic oral acyclovir was used in 13%. Final visual acuity was worse than 0.5 in 17% of the involved eyes and was due to corneal scarring or cataract formation. Patients with iridocyclitis only had no permanent visual loss. Herpetic anterior uveitis is a recurrent granulomatous disease commonly associated with corneal involvement, iris atrophy, and transient intraocular pressure rise. Visual prognosis is good, especially in patients who have only anterior uveitis without corneal disease.

Keywords

Herpetic anterior uveitis Keratouveitis Herpes simplex virus Varicella zoster virus 

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Copyright information

© Springer Science+Business Media B.V. 2010

Authors and Affiliations

  • Ilknur Tugal-Tutkun
    • 1
  • Berna Ötük-Yasar
    • 1
  • Emre Altinkurt
    • 1
  1. 1.Istanbul Faculty of Medicine, Department of OphthalmologyIstanbul UniversityIstanbulTurkey

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