International Ophthalmology

, 29:373 | Cite as

The relationship between central corneal thickness and degree of myopia among Saudi adults

  • Hani S. Al-Mezaine
  • Saleh Al-Obeidan
  • Dustan Kangave
  • Abdulkareem Sadaawy
  • Taher A. Wehaib
  • Saleh A. Al-Amro
Original Paper

Abstract

Purpose To determine the relationship between central corneal thickness (CCT) and myopia among Saudi adults. Methods In a prospective study, the CCT of 982 myopic eyes and 158 emmetropic eyes as a control group was measured using ultrasound pachymetry at the Eye Consultants Center, Riyadh, Saudi Arabia. Result The mean myopic spherical equivalent (SE) was −3.7 ± 2.12 D, range −0.25 to −15.0 D.The mean CCT of the myopic group was 543.8 ± 35.40 μm, while for the emmetropic group it was 545.7 ± 27.6 μm. The difference in mean CCT between the two groups was statistically insignificant (P = 0.5). There was no correlation between CCT and the degree of myopic spherical equivalent (r = −0.014, P = 0.939). Conclusion This clinical study showed that there was no difference in CCT between emmetropic and myopic eyes. CCT did not correlate with the degree of myopia. It seems that the central cornea is not significantly involved in the process of myopic progression.

Keywords

Corneal thickness Myopia Pachymetry Ultrasound 

Notes

Acknowledgments

We would like to thank Bassam Abbara, Hanan Basoudan, Howaida Bakili for thire help with data processing.

References

  1. 1.
    Mishima S (1968) Corneal thickness. Surv Ophthalmol 13:57–96PubMedGoogle Scholar
  2. 2.
    Shah S, Chatterjee A, Mathai M (1999) Relationship between corneal thickness and measured intraocular pressure in a general ophthalmology clinic. Ophthalmology 106:2154–2160. doi:10.1016/S0161-6420(99)90498-0 PubMedCrossRefGoogle Scholar
  3. 3.
    Whiteacre MM, Stein RA, Hassanein K (1993) The effect of corneal thickness on applanation tonometry. Am J Ophthalmol 115:592–596Google Scholar
  4. 4.
    Herndon LW, Choudhri SA, Cox T, Damji K, Shield MB, Allingham R (1997) Central corneal thickness in normal, glaucomatous, and ocular hypertensive eyes. Arch Ophthalmol 115:1137–1141PubMedGoogle Scholar
  5. 5.
    Pallikaris IG, Kymionis GD, Astyrakakis NI (2001) Corneal ectasia induced by laser in situ keratomileusis. J Cataract Refract Surg 27:1796–1802. doi:10.1016/S0886-3350(01)01090-2 PubMedCrossRefGoogle Scholar
  6. 6.
    Binder PS (2003) Ectasia after laser in situ keratomileusis. J Cataract Refract Surg 29:2419–2429. doi:10.1016/j.jcrs.2003.10.012 PubMedCrossRefGoogle Scholar
  7. 7.
    Lin LL, Shih YF, Tsai CB, Chen CJ, Lee LA, Hung PT et al (1999) Epidemiologic study of ocular refraction among schoolchildren in Taiwan in 1995. Optom Vis Sci 76:275–281. doi:10.1097/00006324-199905000-00013 PubMedCrossRefGoogle Scholar
  8. 8.
    Hosaka A (1988) The growth of the eye and its components: Japanese studies. Acta Ophthalmol Suppl 185:65–68PubMedCrossRefGoogle Scholar
  9. 9.
    Hosaka A (1988) Population studies: myopia experience in Japan. Acta Ophthalmol Suppl 185:37–40PubMedCrossRefGoogle Scholar
  10. 10.
    Lin LL, Shih YF, Lee YC, Hung PT, Hou PK (1996) Changes in ocular refraction and its components among medical students-a 5-year longitudinal study. Optom Vis Sci 73:495–498. doi:10.1097/00006324-199607000-00007 PubMedCrossRefGoogle Scholar
  11. 11.
    Curtin BJ (1985) Ocular findings and complications. In: The myopias: basic science and clinical management. Harper and Row, Philadelphia, pp 277–385Google Scholar
  12. 12.
    Celorio JM, Pruett RC (1991) Prevalence of lattice degeneration and its relation to axial length in severe myopia. Am J Ophthalmol 111:20–23PubMedGoogle Scholar
  13. 13.
    Reiner A, Shih YF, Fitzgerald ME (1995) The relationship of choroidal blood flow and accommodation to the control of ocular growth. Vision Res 35:1227–1245. doi:10.1016/0042-6989(94)00242-E PubMedCrossRefGoogle Scholar
  14. 14.
    Funata M, Tokoro T (1990) Scleral change in experimentally myopic monkeys. Graefes Arch Clin Exp Ophthalmol 228:174–179PubMedCrossRefGoogle Scholar
  15. 15.
    Phillips JR, McBrien NA (1995) Form deprivation myopia: elastic properties of sclera. Ophthalmic Physiol Opt 15:357–362. doi:10.1016/0275-5408(95)00062-I PubMedCrossRefGoogle Scholar
  16. 16.
    Kunert KS, Bhartiya P, Tandon R, Dada T, Christian H, Vajpayee RB (2003) Central corneal thickness in Indian patients undergoing LASIK for myopia. J Refract Surg 19:378–379PubMedGoogle Scholar
  17. 17.
    von Bahr G (1956) Corneal thickness: its measurement and changes. Am J Ophthalmol 42:251–266Google Scholar
  18. 18.
    Alsbirk PH (1978) Corneal thickness. 1. Age variation, sex difference and oculometric correlations. Acta Ophthalmol Scand 56:95–104Google Scholar
  19. 19.
    Chang SW, Tsai IL, Hu FR, Shih YF (2001) The cornea in young myopic adults. Br J Ophthalmol 85:916–920. doi:10.1136/bjo.85.8.916 PubMedCrossRefGoogle Scholar
  20. 20.
    Srivannaboon S (2002) Relationship between corneal thickness and level of myopia. J Med Assoc Thai 85:162–166PubMedGoogle Scholar
  21. 21.
    Martola EL, Baum JL (1968) Central and peripheral corneal thickness- a clinical study. Arch Ophthalmol 79:28–30PubMedGoogle Scholar
  22. 22.
    Hansen FK (1971) Clinical study of normal human central corneal thickness. Acta Ophthalmol Scand 49:82–89Google Scholar
  23. 23.
    Ehlers N, Hansen FK (1976) Further data on biometric correlations of central corneal thickness. Acta Ophthalmol Scand 54:774–778Google Scholar
  24. 24.
    Tanaka HM, Mori ES, Maia N, Freitas D, Campos M, Chamon W (1996) Corneal thickness in high myopes. Invest Ophthalmol Vis Sci 37:2566–2566Google Scholar
  25. 25.
    Price FW Jr, Koller DL, Price MO (1999) Central corneal pachymetry in patients undergoing laser in situ keratomileusis. Ophthalmology 106:2216–2220. doi:10.1016/S0161-6420(99)90508-0 PubMedCrossRefGoogle Scholar
  26. 26.
    Cho P, Lam C (1999) Factors affecting the central corneal thickness of Hong Kong Chinese. Curr Eye Res 18:368–374. doi:10.1076/ceyr.18.5.368.5347 PubMedCrossRefGoogle Scholar
  27. 27.
    Liu Z, Pflugfelder SC (2000) The effects of long-term contact lens wear on corneal thickness, curvature, and surface regularity. Ophthalmology 107:105–111. doi:10.1016/S0161-6420(99)00027-5 PubMedCrossRefGoogle Scholar
  28. 28.
    Aghaian E, Choe JE, Lin S, Stamper RL (2004) Central corneal thickness of Caucasians, Chinese, Hispanics, Filipinos, African Americans, and Japanese in a glaucoma clinic. Ophthalmology 111:2211–2219. doi:10.1016/j.ophtha.2004.06.013 PubMedCrossRefGoogle Scholar
  29. 29.
    Oliveira C, Tello C, Liebmann J, Ritch R (2006) Central corneal thickness is not related to anterior scleral thickness or axial length. J Glaucoma 15:190–194. doi:10.1097/01.ijg.0000212220.42675.c5 PubMedCrossRefGoogle Scholar
  30. 30.
    Fam HB, How AC, Baskaran M, Lim KL, Chan YH, Aung T (2006) Central corneal thickness and its relationship to myopia in Chinese adults. Br J Ophthalmol 90:1451–1453. doi:10.1136/bjo.2006.101170 PubMedCrossRefGoogle Scholar
  31. 31.
    European Glaucoma Prevention Study Group, Pfeiffer N, Torri V, Miglior S, Zeyen T, Adamsons I, Cunha-Vaz J (2007) Central corneal thickness in the European Glaucoma Prevention Study. Ophthalmology 114:454–459. doi:10.1016/j.ophtha.2006.07.039 PubMedCrossRefGoogle Scholar
  32. 32.
    Lam CS, Edward M, Millodot M, Goh WS (1999) A 2-year longitudinal study of myopia progression and optical component changes among Hong Kong schoolchildren. Optom Vis Sci 76:370–380. doi:10.1097/00006324-199906000-00016 PubMedCrossRefGoogle Scholar
  33. 33.
    Goss DA, Van veen HG, Rainey BB, Feng B (1997) Ocular component measured by keratometry, phakometry, and ultrasonography in emmetropic and myopic optometry student. Optom Vis Sci 74:489–495. doi:10.1097/00006324-199707000-00015 PubMedCrossRefGoogle Scholar
  34. 34.
    Schoessler JP, Baar JT (1980) Central thickness changes with extended contact lens wear. Am J Optom Physiol Opt 57:729–733PubMedGoogle Scholar
  35. 35.
    Shimmyo M, Orloff PN (2005) Corneal thickness and axial length. Am J Ophthalmol 139:553–554. doi:10.1016/j.ajo.2004.08.061 PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media B.V. 2008

Authors and Affiliations

  • Hani S. Al-Mezaine
    • 1
  • Saleh Al-Obeidan
    • 1
  • Dustan Kangave
    • 2
  • Abdulkareem Sadaawy
    • 3
  • Taher A. Wehaib
    • 3
  • Saleh A. Al-Amro
    • 1
  1. 1.Department of Ophthalmology, College of MedicineKing Saud UniversityRiyadhKingdom of Saudi Arabia
  2. 2.Diabetes Research Center, College of MedicineKing Saud UniversityRiyadhSaudi Arabia
  3. 3.The Eye Consultants CenterRiyadhSaudi Arabia

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