Advertisement

International Ophthalmology

, Volume 27, Issue 6, pp 369–371 | Cite as

Central retinal artery occlusion in an ANCA negative Churg-Strauss syndrome patient

  • Peykan TürkçüoğluEmail author
  • Ahmet Isık
  • Nurettin Deniz
  • Burak Turgut
  • Elif Kılıç Kan
Original Paper

Abstract

Purpose

To describe a central retinal artery occlusion in a patient with antineutrophil cytoplasmic antibody (ANCA) negative Churg-Strauss syndrome.

Methods

Review of clinical and laboratory findings of a 44-year-old woman with ANCA negative Churg-Strauss syndrome that developed sudden vision loss in left eye.

Results

Left central retinal artery occlusion was diagnosed by retinal whitening, a cherry-red spot, and delayed arterial filling on fluorescein angiography. Perinuclear ANCA and cytoplasmic ANCA were negative.

Conclusion

Central retinal artery occlusion can occur in ANCA negative Churg-Strauss syndrome. Patients with this diagnosis should be considered for prophylactic high dose corticosteroid, regardless of their ANCA status.

Keywords

ANCA Central retinal artery occlusion Churg-Strauss syndrome 

References

  1. 1.
    Masi AT, Hunder GG, Lie JT, Michel BA, Bloch DA, Arend WP, Calabrese LH, Edworthy SM, Fauci AS, Leavitt RY et al (1990) The American College of Rheumatology 1990 criteria for the classification of Churg-Strauss syndrome (allergic granulomatosis and angiitis). Arthritis Rheum 33:1094–1100PubMedCrossRefGoogle Scholar
  2. 2.
    Chumbley LC, Harrison EG Jr, DeRemee RA (1977) Allergic granulomatosis and angiitis (Churg-Strauss syndrome). Report and analysis of 30 cases. Mayo Clin Proc 52:477–484PubMedGoogle Scholar
  3. 3.
    Shields CL, Shields JA, Rozanski TI (1986) Conjunctival involvement in Churg-Strauss syndrome. Am J Ophthalmol 102:601–605PubMedGoogle Scholar
  4. 4.
    Androudi S, Iaccheri B, Brazitikos P, Papadaki T, Foster CS (2004) Bilateral chronic anterior uveitis & neuro-ophthalmologic manifestations in a patient with Churg-Strauss syndrome: an unusual ocular presentation. Ocul Immunol Inflamm 12:59–63PubMedCrossRefGoogle Scholar
  5. 5.
    Takanashi T, Uchida S, Arita M, Okada M, Kashii S (2001) Orbital inflammatory pseudotumor and ischemic vasculitis in Churg-Strauss syndrome: report of two cases and review of the literature. Ophthalmology 108:1129–1133PubMedCrossRefGoogle Scholar
  6. 6.
    Chen SD, Lochhead J, Satchi K, Patel CK, Frith P (2005) Bilateral retinal venous occlusion and unilateral cystoid macular edema in Churg-Strauss syndrome treated with intravitreal triamcinolone. Retina 25:655–657PubMedCrossRefGoogle Scholar
  7. 7.
    Udono T, Abe T, Sato H, Tamai M (2003) Bilateral central retinal artery occlusion in Churg-Strauss syndrome. Am J Ophthalmol 136:1181–1183PubMedCrossRefGoogle Scholar
  8. 8.
    Partal A, Moshfeghi DM, Alcorn D (2004) Churg-Strauss syndrome in a child: retina and optic nerve findings. Br J Ophthalmol 88:971–972PubMedCrossRefGoogle Scholar
  9. 9.
    Stubiger N, Schlote T, Kotter I, Zierhut M (1999) Churg-Strauss syndrome. Klin Monatsbl Augenheilkd 214:171–174PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media, Inc. 2007

Authors and Affiliations

  • Peykan Türkçüoğlu
    • 1
    Email author
  • Ahmet Isık
    • 2
  • Nurettin Deniz
    • 1
  • Burak Turgut
    • 1
  • Elif Kılıç Kan
    • 2
  1. 1.Department of OphthalmologyFırat University School of MedicineElazığTurkey
  2. 2.Department of Internal MedicineFırat University School of MedicineElazığTurkey

Personalised recommendations