International Ophthalmology

, Volume 27, Issue 2–3, pp 81–85 | Cite as

Pathology of Vogt–Koyanagi–Harada disease

  • Narsing A. Rao
Original Paper


Typical histopathologic features of Vogt–Koyanagi–Harada disease (VKH) include granulomatous panuveitis with preservation of the choriocapillaris and exudative retinal detachment. In the chronic stage of the disease, however, histologic changes consist of nongranulomatous uveitis followed, in the chronic recurrent stage, by granulomatous uveitis and involvement of the choriocapillaris. In chronic VKH the peripheral fundus scars are not Dalén–Fuchs nodules; they are, instead, indicative of focal chorioretinal atrophy with loss of retinal pigment epithelium.


Granulomatous uveitis Vogt–Koyanagi–Harada disease Sympathetic ophthalmia Pathology Choriocapillaris 



Supported in part by NEI core grant EY0 13040 and by a grant from Research to Prevent Blindness, New York, New York.


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Copyright information

© Springer Science+Business Media, Inc. 2007

Authors and Affiliations

  1. 1.Doheny Eye InstituteLos AngelesUSA

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