, Volume 30, Issue 6, pp 244–249 | Cite as

The Effects of Anti-Adhesion Materials in Preventing Postoperative Adhesion in Abdominal Cavity (Anti-Adhesion Materials for Postoperative Adhesions)

  • Mustafa Sahin
  • Murat Cakir
  • Fatih Mehmet Avsar
  • Ahmet Tekin
  • Tevfik Kucukkartallar
  • Mehmet Akoz



The purpose of this study was to compare the effects of anti-adhesion materials in postoperative adhesions.

Materials and Methods

Rats were assigned to five groups: Group 1: Control. Group 2: chitin layers were used. Group 3: Na-hyaluronate / carboxymethylcellulose layers were used. Group 4: Na-hyaluronate gel was poured into the abdomen. Group 5: methylprednisolone was injected. The adhesion frequency and grade were scored according to Granat. Blood was taken for Hb, AST, BUN and albumin levels determination.


The adhesion frequencies (right and left) and grades were as follow in Groups; I: 82%, 91%, 2.63 ± 1.22; II: 8.3%, 25%, 0.58 ± 0.66; III: 17%, 33%, 1.08 ± 1.08; IV: 50%, 58%, 1.41 ± 1.44; V: 50%, 42%, 1.41 ± 1.50. The adhesion phase in all study groups was found significantly low compared to control group, p < 0.05. No difference was observed among serologic and hematological parameters in all groups.


All the materials used significantly lowered the adhesion frequency and grade.

Key words

postoperative adhesion anti-adhesion materials abdominal cavity 


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Copyright information

© Springer Science+Business Media, LLC 2007

Authors and Affiliations

  • Mustafa Sahin
    • 1
  • Murat Cakir
    • 1
  • Fatih Mehmet Avsar
    • 2
  • Ahmet Tekin
    • 1
    • 4
  • Tevfik Kucukkartallar
    • 1
  • Mehmet Akoz
    • 3
  1. 1.Department of General SurgerySelcuk University Meram Medical FacultyKonyaTurkey
  2. 2.Department of Surgical Emergency ServiceAnkara Numune Training and Research HospitalAnkaraTurkey
  3. 3.Department of BiochemistrySelcuk University Meram Medical FacultyKonyaTurkey
  4. 4.KonyaTurkey

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