Hydrobiologia

, Volume 532, Issue 1–3, pp 221–224 | Cite as

Endocrine disruption in the pituitary of white sucker (Catostomus commersoni) caged in a lake contaminated with iron-ore mine tailings

  • Goverdina E. Fåhræus-van ree
  • Jerry F. Payne
Short Research Note

Abstract

Immunohistochemical analysis revealed that white suckers caged in Lake Wabush, which receives a high volume of iron ore tailings, had significantly lower levels of growth hormone per pituitary area than fish caged in an adjoining reference lake, Lake Shabogamo. This demonstrates that the pituitary could be a target to consider in endocrine studies. The findings are also novel with respect to the ecotoxicological potential of mining effluents.

Keywords

gonadotropic hormone growth hormone immunocytochemistry iron-ore tailings pituitary white sucker 

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References

  1. Arcand-Hoy, L. D., Benson, W. H. 1998Fish reproduction: an ecologically relevant indicator of endocrine disruptionEnvironmental Toxicology and Chemistry174957Google Scholar
  2. Chang, L. W.Magos, L.Suzuki, T. eds. 1996Toxicology of MetalsLewis PublishersNew York1198Google Scholar
  3. Fox, M. R. S., Rader, J. I. 1988

    Iron

    Seiler, H. G.Sigel, H. eds. Handbook on Toxicity of Inorganic CompoundsMarcel Dekker, IncNew York345354
    Google Scholar
  4. Hamoutene, D., Rahimtula, A., Payne, J. 2000Iron ore mines leachate potential for oxyradical productionEcotoxicology and Environmental Safety46218224PubMedGoogle Scholar
  5. Holmes, R. L., Ball, J. N. 1974The Pituitary Gland: A Comparative AccountCambridge University PressNew York, USA397Google Scholar
  6. Kime, D. E. 1998Endocrine Disruption in FishKluwer Academic PublishersBoston396Google Scholar
  7. Le Gac, F., Blaise, O., Fostier, A., Le Bail, P., Loir, M., Mourot, B., Weil, C. 1993Growth hormone (GH) and reproduction: a reviewFish Physiology and Biochemistry11219232Google Scholar
  8. Luna, L. G. 1968Manual of Histologic Staining Methods of the Armed Forces Institute of Pathology. 3rd edMcGraw-Hill Book CompanyNew York258Google Scholar
  9. Mommsen, T. P. 2001Review paradigms of growth in fishComparative Biochemistry and Physiology Part B129207219Google Scholar
  10. Payne, J. F., Malins, D. C., Gunselman, S., Rahimtula, A., Yeats, P. A. 1998DNA oxidative damage and vitamin A reduction in fish from a large lake system in Labrador, Newfoundland, contaminated with iron-ore mine tailingsMarine Environmental Research46289294Google Scholar
  11. Payne, J. F., French, B., Hamoutene, D., Yeats, P., Rahimtula, A., Scruton, D., Andrews, C. 2001Are metal mining effluent regulations adequate: identification of a novel bleached fish syndrome in association with iron-ore mining effluents in Labrador, NewfoundlandAquatic Toxicology52311317PubMedGoogle Scholar
  12. Poirier, L. A., Littlefield, N. A. 1996

    Metal interactions in chemical carcinogenesis

    Chang, L. W.Magos, L.Suzuki T, T. eds. Toxicology of MetalsLewis PublishersNew York289298
    Google Scholar
  13. Sheenan, D. C., Hrapchak, B. B. 1980Theory and Practice of HistotechnologyThe C.V. Mosby CompanyToronto320323Google Scholar
  14. Van Ree, G. E. 1977In vivo and in vitro studies of the pituitary ovary axis in the zebrafish (Brachydanio rerio Ham. Buch.)State University of UtrechtUtrecht, The NetherlandsPh.D. ThesisGoogle Scholar

Copyright information

© Springer 2005

Authors and Affiliations

  • Goverdina E. Fåhræus-van ree
    • 1
  • Jerry F. Payne
    • 2
  1. 1.Department of BiologyMemorial University of NewfoundlandSt. John’s, Newfoundland and LabradorCanada
  2. 2.Department of Fisheries and OceansMemorial University of NewfoundlandSt. John’s, Newfoundland and LabradorCanada

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