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Flow-mediated dilation and heart failure: a review with implications to physical rehabilitation

  • G. P. T. Areas
  • A. Mazzuco
  • F. R. Caruso
  • R. B. Jaenisch
  • R. Cabiddu
  • S. A. Phillips
  • R. Arena
  • A. Borghi-Silva
Article
  • 154 Downloads

Abstract

Endothelial dysfunction plays as an important role on mismatch responses that occur during exercise in patients with congestive heart failure (CHF). However, cardiac rehabilitation, a core component of management of CHF patients, can improve endothelial function, contributing to reduce the morbidity and mortality of these patients. The primary aims of this review were to describe the importance of flow-mediated dilatation (FMD) as a non-invasive validation tool to assess endothelial dysfunction and to highlight the relevance of scientific studies that evaluated the effects of exercise interventions on peripheral vascular endothelial function as measured by FMD in patients with CHF with both preserved and reduced ejection fraction.

Keywords

Endothelial function Exercise Physical training Cardiac rehabilitation Heart failure 

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© Springer Science+Business Media, LLC, part of Springer Nature 2018

Authors and Affiliations

  • G. P. T. Areas
    • 1
    • 2
  • A. Mazzuco
    • 2
  • F. R. Caruso
    • 2
  • R. B. Jaenisch
    • 3
  • R. Cabiddu
    • 4
  • S. A. Phillips
    • 5
  • R. Arena
    • 5
  • A. Borghi-Silva
    • 2
  1. 1.Physiological Science DepartamentUniversidade Federal do AmazonasManausBrazil
  2. 2.Cardiopulmonary Physiotherapy LaboratoryUniversidade Federal de Sao CarlosSao CarlosBrazil
  3. 3.Universidade Federal de Santa MariaSanta MariaBrazil
  4. 4.Biomedical EngineeringPolitecnico di MilanoMilanItaly
  5. 5.University of Illinois at ChicagoChicagoUSA

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